Structure

Fmoc-Tyr(PO(OBzl)OH)-OH

CAS
191348-16-0
Catalog Number
ACM191348160-1
Category
Amino Acids
Molecular Weight
573.53
Molecular Formula
C31H28NO8P

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Specification

Description
An excellent building block for the preparation of phosphotyrosine-containing peptides by Fmoc SPPS. This derivative can be introduced using standard activation methods, such as PyBOPand TBTU. Using this reagent, even peptides containing multiple phosphorylation sites have been prepared efficiently by standard Fmoc SPPS methods.
Synonyms
Fmoc-Tyr(PO(OBzl)OH)-OH, N-α-Fmoc-O-benzyl-L-phosphotyrosine
InChI
1S/C31H28NO8P/c33-30(34)29(18-21-14-16-23(17-15-21)40-41(36,37)39-19-22-8-2-1-3-9-22)32-31(35)38-20-28-26-12-6-4-10-24(26)25-11-5-7-13-27(25)28/h1-17,28-29H,18-20H2,(H,32,35)(H,33,34)(H,36,37)/t29-/m0/s1
InChI Key
WNFKGEXQEWKECX-LJAQVGFWSA-N
Melting Point
90-105℃
Application
Peptide synthesis.
Assay
≥90.0% (acidimetric)
≥95% (TLC)
≥95.0% (HPLC)
Form
powder
Functional Group
Fmoc
Quality Level
200
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Storage Temperature
15-25℃
Type
Unusual Amino Acids, Phosphorylated Amino Acids
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