Structure

Fmoc-Phe(4-NO₂)-OH

CAS
95753-55-2
Catalog Number
ACM95753552
Category
Amino Acids
Molecular Weight
432.43

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Specification

Description
Cleavage and Deprotection Protocols for Fmoc SPPS.
Synonyms
Fmoc-Phe(4-NO₂)-OH, N-α-Fmoc-4-nitro-L-phenylalanine
InChI
1S/C24H20N2O6/c27-23(28)22(13-15-9-11-16(12-10-15)26(30)31)25-24(29)32-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,25,29)(H,27,28)/t22-/m0/s1
InChI Key
RZRRJPNDKJOLHI-QFIPXVFZSA-N
Melting Point
213-223℃
Application
Peptide synthesis.
Assay
≥95.0% (acidimetric)
≥97.0% (HPLC)
≥98% (TLC)
Form
powder
Functional Group
Fmoc
MDL Number
MFCD00057810
Quality Level
200
Reaction Suitability
reaction type: Fmoc solid-phase peptide synthesis
Storage Temperature
2-30℃

Upstream Synthesis Route 1

  • 949-99-5
  • 82911-69-1
  • 95753-55-2

Reference: [1] Tetrahedron Letters, 1999, vol. 40, # 36, p. 6557 - 6560
[2] Russian Journal of Organic Chemistry, 2016, vol. 52, # 11, p. 1681 - 1685[3] Zh. Org. Khim., 2016, vol. 52, # 11, p. 1686 - 1690,5

Upstream Synthesis Route 2

  • 28920-43-6
  • 949-99-5
  • 95753-55-2

Reference: [1]Journal of the Chemical Society. Perkin transactions II,1984,p. 1723 - 1728
[2]Bioorganic and Medicinal Chemistry Letters,1997,vol. 7,p. 715 - 718

Downstream Synthesis Route 1

  • 95753-55-2
  • 95753-56-3

Reference: [1] Bioorganic and Medicinal Chemistry Letters, 1997, vol. 7, # 6, p. 715 - 718

Downstream Synthesis Route 2

  • 95753-55-2
  • 95753-56-3

Reference: [1] Russian Journal of Organic Chemistry, 2016, vol. 52, # 11, p. 1681 - 1685[2] Zh. Org. Khim., 2016, vol. 52, # 11, p. 1686 - 1690,5

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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