Fmoc-NH-(PEG)10-CH2CH2COOH

• CAS: 2101563-45-3
• Catalog Number: ACM2101563453-1
• Category: Amino Acids
• Molecular Weight: 751.8
• Molecular Formula: C38H57NO14
• Description: Fmoc-NH-PEG10-CH2CH2COOH is a derivative of polyethylene glycol (PEG) that has been modified with a terminal carboxylic acid group and a base-labile 9-Fluorenylmethoxycarbonyl (Fmoc) protecting group. PEG is a biocompatible and highly hydrophilic polymer that is widely used in various biomedical applications due to its excellent solubility, low toxicity, and resistance to protein binding. The addition of a carboxylic acid group to PEG improves its water solubility and allows for conjugation to amino-containing molecules, such as peptides or proteins. The Fmoc protecting group is widely used in solid-phase peptide synthesis to protect the N-terminal amine group of amino acids from undesired side reactions during chain assembly.
• Synonyms: 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34-undecaoxa-4-azaheptatriacontan-37-oic acid
• IUPAC Name: 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
• Canonical SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O
• InChI: 1S/C38H57NO14/c40-37(41)9-11-43-13-15-45-17-19-47-21-23-49-25-27-51-29-30-52-28-26-50-24-22-48-20-18-46-16-14-44-12-10-39-38(42)53-31-36-34-7-3-1-5-32(34)33-6-2-4-8-35(33)36/h1-8,36H,9-31H2,(H,39,42)(H,40,41)
• InChI Key: NAILXQLIMFAMGQ-UHFFFAOYSA-N
• Boiling Point: 826.4±65.0 ℃at 760 mmHg
• Flash Point: 453.6±34.3 ℃
• Density: 1.2±0.1 g/cm³
• Application: Fmoc-NH-PEG10-CH2CH2COOH has a wide range of applications in scientific experiments, including drug delivery, diagnostics, and imaging. Its hydrophilic and biocompatible nature makes it an ideal polymer for the synthesis of nanoparticles or micelles that can carry hydrophobic drugs and improve their solubility and bioavailability in biological systems. Its carboxylic acid group can also be used for the conjugation of various targeting ligands, such as antibodies or peptides, that can improve the specificity and efficiency of drug delivery.
• Exact Mass: 751.37793
• Functional Group: Fmoc
• LogP: 0.15
• MDL Number: MFCD28122954
• Refractive Index: 1.522
• Storage Temperature: 4 ℃
• Type: Unusual Amino Acids, Pegylated Amino Acids & Special Linkers
• Vapor Pressure: 0.0±3.2 mmHg at 25℃