Structure

Fmoc-5-bromo-DL-tryptophan

CAS
925939-82-8
Catalog Number
ACM925939828
Category
Amino Acids
Molecular Weight
505.4
Molecular Formula
C26H21BrN2O4

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Specification

Description
Fmoc-Br-Trp is a synthetic amino acid that has an Fmoc-protecting group, which is commonly used in peptide synthesis. Fmoc is a stable and easily removable amino-protecting group that provides high yields in chemical reactions. Bromine is a halogen atom that has unique chemical properties, including high electronegativity, reactivity, and isotope effect. Tryptophan is an aromatic amino acid that has a bulky indole ring and a polar side chain. This combination of Fmoc, bromine, and tryptophan makes Fmoc-Br-Trp a versatile and useful building block for peptide synthesis.
Synonyms
5-Bromo-N-[(9H-fluoren-9-ylmethoxy)carbonyl]tryptoph
IUPAC Name
3-(5-bromo-1H-indol-3-yl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CNC5=C4C=C(C=C5)Br)C(=O)O
InChI
1S/C26H21BrN2O4/c27-16-9-10-23-21(12-16)15(13-28-23)11-24(25(30)31)29-26(32)33-14-22-19-7-3-1-5-17(19)18-6-2-4-8-20(18)22/h1-10,12-13,22,24,28H,11,14H2,(H,29,32)(H,30,31)
InChI Key
OAIIUHJPRPJYHV-UHFFFAOYSA-N
Application
Fmoc-Br-Trp and its derivatives have various applications in scientific experiments, including peptide synthesis, drug discovery, biomaterials, and bioimaging.
Exact Mass
504.068
Functional Group
Fmoc
HS Code
2933990090
LogP
5.6692
MDL Number
MFCD02682357
PSA
94.91
Storage Temperature
4 ℃
Type
Unusual Amino Acids, Analogs of Tryptophan
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