Fmoc-Asn(Dmcp)-OH

• CAS: 172947-19-2
• Catalog Number: ACM172947192
• Category: Amino Acids
• Molecular Weight: 436.5
• Description: A superior derivative to Fmoc-Asn(Trt)-OH for the synthesis of Asn-containing peptides by Fmoc SPPS. Fmoc-Asn(Dmcp)-OH is more soluble in DMF than Fmoc-Asn(Trt)-OH, thereby facilitating coupling reactions at higher concentration. Cleavage of the Dmcp group is rapid, even when the residue is located at the N-terminus of a peptide. Coupling of Dmcp-protected derivatives is faster than that of the corresponding hindered Trt derivatives. Dmcp-protected peptides have enhanced solubility.
• Synonyms: Fmoc-Asn(Dmcp)-OH, N-α-Fmoc-N-β-(1-cyclopropyl-1-methylethyl)-L-asparagine
• Application: Peptide synthesis.
• Assay: ≥95.0% (acidimetric); ≥98.0% (HPLC); ≥98.0% (TLC)
• Form: powder
• Functional Group: amide
• Quality Level: 200
• Reaction Suitability: reaction type: Fmoc solid-phase peptide synthesis
• Storage Temperature: 15-25℃