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Structure

Fmoc-4-amino-3-hydroxybutanoic acid

CAS
184763-08-4
Catalog Number
ACM184763084
Category
Amino Acids
Molecular Weight
341.4
Molecular Formula
C19H19NO5

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Specification

Description
Fmoc-4-amino-3-hydroxybutanoic acid (Fmoc-Ahb-OH) is a type of amino acid that contains both an amino group and a carboxyl group. It is commonly used as a building block for peptides, which are short chains of amino acids linked by peptide bonds.
IUPAC Name
4-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxybutanoic acid
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCC(CC(=O)O)O
InChI
1S/C19H19NO5/c21-12(9-18(22)23)10-20-19(24)25-11-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,12,17,21H,9-11H2,(H,20,24)(H,22,23)
InChI Key
KAVHFNYDXGWPBX-UHFFFAOYSA-N
Application
Fmoc-Ahb-OH is widely used in the synthesis of peptides for various scientific applications. The inclusion of Ahb-OH in peptide chains can result in improved bioactivity or stability of the peptides. For example, Ahb-OH can be used to add hydrophilic or amphiphilic characters to peptides, which can enhance their solubility or cell penetration. Ahb-OH can also be used to introduce functional groups that can be used for further modification of the peptide.
Exact Mass
341.126
Functional Group
Fmoc
HS Code
2922509090
LogP
2.5651
MDL Number
MFCD02682575
PSA
99.35
Storage Temperature
4 ℃
Type
Unusual Amino Acids, Analogs of Serine, Threonine, and Statine
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