Specification
Synonyms
(±)-2-Amino-3-(4-imidazolyl)propionic acid
Canonical SMILES
NC(Cc1c[nH]cn1)C(O)=O
InChI
1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)
InChI Key
HNDVDQJCIGZPNO-UHFFFAOYSA-N
Melting Point
273 ℃(dec.) (lit.)
Solubility
0.5 M HCl: soluble
Application
DL-Histidine has been used to study the fouling behaviour of polyethersulfone ultrafiltration membranes made with different PVP (polyvinylpyrrolidone).
Biochem Physiol Actions
L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.
Technique
ligand binding assay: suitable