1,3-Diphenyl-4,5-dihydro-1H-pyrazole

• CAS: 2538-52-5
• Catalog Number: ACM2538525
• Category: Other Products
• Molecular Weight: 222.2851
• Molecular Formula: C15H14N2
• Description: 1,3-Diphenyl-4,5-dihydro-1H-pyrazole is a heterocyclic compound belonging to the pyrazole family. It is an organic compound composed of two phenyl rings, a nitrogen atom and a hydrogen atom. Pyrazoles are known for their versatile properties, which makes them useful in a wide range of applications. DPDP is of particular interest due to its potential applications in scientific and medical research.
• Synonyms: 1,3-Diphenylpyrazoline, 1,3-Diphenyl-2-pyrazoline, 2-Pyrazoline, 1,3-diphenyl-, MLS000717825, 1,3-Diphenyl-4,5-dihydro-1H-pyrazole, MolPort-001-631-521, NSC186211, NSC625226, AIDS132054, AIDS-132054, 1,3-Diphenyl-.DELTA.2-pyrazoline, CID302304, ZINC04142401, 1H-Pyrazole, 4,5-dihydro-1,3-diphenyl-, BAS 00363868, SMR000279193, AE-848/30721014, A0944/0044214, 2538-52-5
• IUPAC Name: 2,5-diphenyl-3,4-dihydropyrazole
• Canonical SMILES: C1CN(N=C1C2=CC=CC=C2)C3=CC=CC=C3
• InChI: InChI=1S/C15H14N2/c1-3-7-13(8-4-1)15-11-12-17(16-15)14-9-5-2-6-10-14/h1-10H,11-12H2
• InChI Key: ZWCZPVMIHLKVLD-UHFFFAOYSA-N
• Boiling Point: 351.9ºC at 760mmHg
• Flash Point: 166.6ºC
• Density: 1.08g/mL
• Solubility: <0.2 ug/mL (The mean of the results at pH 7.4)
• Application: 1,3-Diphenyl-4,5-dihydro-1H-pyrazole is a versatile compound that can be used in a variety of scientific research applications. It has been used as a ligand for the binding of metal ions, such as copper, zinc, and iron, in order to study the structure and function of metalloproteins. It has also been used as a fluorescent probe for the study of enzyme kinetics, as well as for the detection of reactive oxygen species. In addition, 1,3-Diphenyl-4,5-dihydro-1H-pyrazole has been used as a reactant in organic syntheses, and as a catalyst in the synthesis of various pharmaceuticals.
• Storage: Store at 2-8 ℃
• Exact Mass: 222.116
• H-Bond Acceptor: 2
• H-Bond Donor: 0
• PSA: 15.6
• Refractive Index: 1.613
• Vapor Pressure: 3.98E-05mmHg at 25°C
• XLogP3: 2.8016

Case Study

Application of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole in the synthesis of 1,3-Diarylpyrazoles

Thuyet L. D. Pham, et al. Synlett 2020; 31(08): 801-804.

A copper-promoted coupling of phenylacetone and arylhydrazine was developed for the synthesis of 1,3-diarylpyrazoles from commercial substrates and/or simple transformations.
The reactions afforded substituted pyrazoles in the presence of TEMPO oxidant, acetic acid additive, and DMF solvent. A number of functionalities were compatible with reaction conditions, including halogens, methoxy, trifluoromethyl, and nitro groups. An indazole could be obtained if an electron-poor propiophenone was used.

Custom Q&A

What is the molecular formula of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole?

The molecular formula of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole is C15H14N2.

What is the molecular weight of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole?

The molecular weight of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole is 222.28 g/mol.

When was 1,3-Diphenyl-4,5-dihydro-1H-pyrazole created?

1,3-Diphenyl-4,5-dihydro-1H-pyrazole was created on March 26, 2005.

What is the IUPAC name of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole?

The IUPAC name of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole is 2,5-diphenyl-3,4-dihydropyrazole.

What is the InChI of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole?

The InChI of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole is InChI=1S/C15H14N2/c1-3-7-13(8-4-1)15-11-12-17(16-15)14-9-5-2-6-10-14/h1-10H,11-12H2.

What is the InChIKey of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole?

The InChIKey of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole is ZWCZPVMIHLKVLD-UHFFFAOYSA-N.

What is the canonical SMILES of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole?

The canonical SMILES of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole is C1CN(N=C1C2=CC=CC=C2)C3=CC=CC=C3.

What is the CAS number of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole?

The CAS number of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole is 2538-52-5.

What is the ChEMBL ID of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole?

The ChEMBL ID of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole is CHEMBL1305810.

What is the topological polar surface area of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole?

The topological polar surface area of 1,3-Diphenyl-4,5-dihydro-1H-pyrazole is 15.6Ų.