3',4'-Dimethoxyflavone

• CAS: 4143-62-8
• Catalog Number: ACM4143628
• Category: Inhibitors
• Molecular Weight: 282.3
• Molecular Formula: C17H14O4
• Description: 3',4'-Dimethoxyflavone is a lipophilic flavone, can be isolated from the leaves of Primula veris. 3',4'-Dimethoxyflavone can reduce the synthesis and accumulation of PARP and protect cortical neurones against cell death induced by Parthanatos. 3',4'-Dimethoxyflavone is also an aryl hydrocarbon receptor antagonist in human breast cancer cells. 3',4'-Dimethoxyflavone can promote the proliferation of human hematopoietic stem cells. 3',4'-Dimethoxyflavone has various biological activities, including antioxidant, anti-cancer, anti-inflammatory, anti-atherogenic, hypolipidaemic, and neuroprotective or neurotrophic effects.
• Synonyms: 3,4-DIMETHOXYFLAVONE; 2-(3,4-Dimethoxyphenyl)chromen-4-one; 2-(3,4-dimethoxyphenyl)chromen-4-one
• IUPAC Name: 2-(3,4-dimethoxyphenyl)chromen-4-one
• Canonical SMILES: COC1=C(C=C(C=C1)C2=CC(=O)C3=CC=CC=C3O2)OC
• InChI: InChI=1S/C17H14O4/c1-19-15-8-7-11(9-17(15)20-2)16-10-13(18)12-5-3-4-6-14(12)21-16/h3-10H,1-2H3
• InChI Key: ZGHORMOOTZTQFL-UHFFFAOYSA-N
• Boiling Point: 428.5ºC at 760 mmHg
• Melting Point: 154-155ºC
• Flash Point: 190.6ºC
• Density: 1.242g/cm³
• Appearance: Powder
• Storage: Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
• Exact Mass: 282.08900
• H-Bond Acceptor: 4
• H-Bond Donor: 0
• Safety Description: S22-S24/25
• Shipping: Can be shipped at room temperature, where not in use may vary.
• Source: PlantsEuphorbiaceaeEuphorbia hirta L.Plantsother families