D-Galactosamine pentaacetate

• CAS: 76375-60-5
• Catalog Number: ACM76375605
• Category: Other Products
• Molecular Weight: 389.35
• Molecular Formula: C16H23NO10
• Synonyms: 2-Acetamido-2-deoxy-b-D-galactopyranose 1,3,4,6-tetra-O-acetyl
• IUPAC Name: [(2R,3R,4R,5R)-5-acetamido-3,4,6-triacetyloxyoxan-2-yl]methyl acetate
• Canonical SMILES: CC(=O)N[C@@H]1[C@H]([C@H]([C@H](OC1OC(=O)C)COC(=O)C)OC(=O)C)OC(=O)C
• InChI: InChI=1S/C16H23NO10/c1-7(18)17-13-15(25-10(4)21)14(24-9(3)20)12(6-23-8(2)19)27-16(13)26-11(5)22/h12-16H,6H2,1-5H3,(H,17,18)/t12-,13-,14+,15-,16?/m1/s1
• InChI Key: OVPIZHVSWNOZMN-IWQYDBTJSA-N
• Melting Point: 230 °C (dec.)
• Density: 1.30±0.1 g/ml
• Appearance: White to off-white solid
• pKa: 13.41±0.70

Synthetic Use

Downstream Synthesis Route 1

• 76375-60-5

• 10378-06-0

Reference: [1]Hofmeister, Armin; Jahn-Hofmann, Kerstin; Brunner, Bodo; Helms, Mike W.; Metz-Weidmann, Christiane; Krack, Arne; Kurz, Michael; Li, Ziyu; Weitzenberg, Merle M.; Pflimlin, Elsa; Plettenburg, Oliver; Scheidler, Sabine
[Journal of Medicinal Chemistry, 2021, vol. 64, # 10, p. 6838 - 6855]

Downstream Synthesis Route 2

• 76375-60-5

• 41355-44-6

Reference: [1]Location in patent: experimental part
Stokmaier, Daniela; Khorev, Oleg; Cutting, Brian; Born, Rita; Ricklin, Daniel; Ernst, Thomas O.G.; Boeni, Fabienne; Schwingruber, Kathrin; Gentner, Martin; Wittwer, Matthias; Spreafico, Morena; Vedani, Angelo; Rabbani, Said; Schwardt, Oliver; Ernst, Beat
[Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 20, p. 7254 - 7264]

Downstream Synthesis Route 3

• 76375-60-5

• 108320-87-2

Reference: [1]Masuko, Sayaka; Bera, Smritilekha; Green, Dixy E.; Weiwer, Michel; Liu, Jian; Deangelis, Paul L.; Linhardt, Robert J.
[Journal of Organic Chemistry, 2012, vol. 77, # 3, p. 1449 - 1456]

* For details of the synthesis route, please refer to the original source to ensure accuracy.