Cortisone Acetate

CAS

50-04-4

Catalog Number

ACM50044

Category

Steroidal Compounds

Molecular Weight

402.48

Molecular Formula

C23H30O6

MSDS COA Spec Sheet

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Specification

Synonyms

4-Pregnene-17α,21-diol-3,11,20-trione 21-acetate; 21-Acetoxy-4-pregnen-17α-ol-3,11,20-trione; [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate; 17α,21-Dihydroxy-4-pregnene-3,11,20-trione 21-acetate; Cortisone Acetate;

IUPAC Name

[2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl]acetate

Canonical SMILES

CC(=O)OCC(=O)C1(CCC2C1(CC(=O)C3C2CCC4=CC(=O)CCC34C)C)O

InChI Key

ITRJWOMZKQRYTA-RFZYENFJSA-N

Boiling Point

577.3ºC at 760mmHg

Melting Point

237-240ºC

Flash Point

197.3ºC

Density

1.26g/cm³

Appearance

solid

EC Number

200-006-5

Exact Mass

402.20400

Safety Description

S22-S36/37

Stability

Stable. Incompatible with strong oxidizing agents.

WGK Germany

What is the molecular formula of cortisone acetate?

The molecular formula of cortisone acetate is C23H30O6.

When was cortisone acetate first isolated?

Cortisone acetate was first isolated in 1935.

What is the IUPAC name of cortisone acetate?

The IUPAC name of cortisone acetate is [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate.

What is the molecular weight of cortisone acetate?

The molecular weight of cortisone acetate is 402.5 g/mol.

How does cortisone acetate bind to nuclear glucocorticoid receptors?

Cortisone acetate diffuses through the cell membrane and binds to nuclear glucocorticoid receptors.

What are the therapeutic uses of cortisone acetate?

Cortisone acetate is used to treat a number of inflammatory conditions such as endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, and gastrointestinal diseases and disorders.

When was cortisone acetate granted FDA approval?

Cortisone acetate was granted FDA approval on June 13, 1950.

What is the InChIKey of cortisone acetate?

The InChIKey of cortisone acetate is ITRJWOMZKQRYTA-RFZYENFJSA-N.

What is the CAS number of cortisone acetate?

The CAS number of cortisone acetate is 50-04-4.

What is the XLogP3 value of cortisone acetate?

The XLogP3 value of cortisone acetate is 2.1.