Cis-2,5-Bishydroxymethyl-Tetrahydrofuran

• CAS: 2144-40-3
• Catalog Number: ACM2144403
• Category: Other Products
• Molecular Weight: 132.16
• Molecular Formula: C6H12O3
• Synonyms: (5-HydroxyMethyl-tetrahydro-furan-2-yl)-Methanol
• IUPAC Name: [(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]methanol
• Canonical SMILES: C1C[C@H](O[C@H]1CO)CO
• InChI: InChI=1S/C6H12O3/c7-3-5-1-2-6(4-8)9-5/h5-8H,1-4H2/t5-,6+
• InChI Key: YCZZQSFWHFBKMU-OLQVQODUSA-N
• Boiling Point: 261.6 °C
• Melting Point: ＜-50 °C
• Density: 1.130 g/ml
• Appearance: Colorless liquid
• pKa: 14.14±0.10

Synthetic Use

Upstream Synthesis Route 1

• 67-47-0

• 2144-40-3

Reference: [1]Cope; Baxter
[Journal of the American Chemical Society, 1955, vol. 77, p. 393,395]
Haworth et al.
[Journal of the Chemical Society, 1945, p. 1,3]
[2]Turner et al.
[Analytical Chemistry, 1954, vol. 26, p. 898]

Upstream Synthesis Route 2

• 1472-01-1

• 2144-40-3

Reference: [1]Nakazaki, Masao; Naemura, Koichiro; Makimura, Masaru; Matsuda, Atsushi; Kawano, Takaaki; Ohta, Yoshihiro
[Journal of Organic Chemistry, 1982, vol. 47, # 12, p. 2429 - 2435]
[2]Cope; Baxter
[Journal of the American Chemical Society, 1955, vol. 77, p. 393,395]

Downstream Synthesis Route 1

• 2144-40-3
• 64-19-7

• 98559-48-9

Reference: [1]Gryszkiewicz-Trochimowski et al.
[Bulletin de la Societe Chimique de France, 1958, p. 610,615]

* For details of the synthesis route, please refer to the original source to ensure accuracy.