Chromeceptin

• CAS: 331859-86-0
• Catalog Number: ACM331859860
• Category: Inhibitors
• Molecular Weight: 359.35
• Molecular Formula: C19H16F3N3O
• Description: Chromeceptin is an IGF2 inhibitor. Chromeceptin inhibits Insulin-like growth factor 2 (IGF2) signaling by a process that begins with chromeceptin binding to multifunctional protein 2 (MFP-2). This interaction stimulates the expression of IGF binding protein 1 (IGFBP-1) and suppressor of cytokine signaling-3 (SOCS-3), both of which activate signal transducers and activators of transcription 6 (STAT6) to attenuate IGF signals.
• Synonyms: Chromeceptin; 94G6
• IUPAC Name: 2-Amino-3-cyano-7-dimethylamino-4-(3-trifluoromethylphenyl)-4H-chromene
• Canonical SMILES: FC(C1=CC(C2C(C#N)=C(N)OC3=C2C=CC(N(C)C)=C3)=CC=C1)(F)F
• InChI: InChI=1S/C19H16F3N3O/c1-25(2)13-6-7-14-16(9-13)26-18(24)15(10-23)17(14)11-4-3-5-12(8-11)19(20,21)22/h3-9,17H,24H2,1-2H3
• InChI Key: GVINXTXGDDSXFQ-UHFFFAOYSA-N
• Solubility: To be determined
• Appearance: Solid powder
• Shelf Life: >2 years if stored properly
• Storage: Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).
• Drug Formulation: To be determined
• Elemental Analysis: C, 63.51; H, 4.49; F, 15.86; N, 11.69; O, 4.45
• Exact Mass: 359.1245
• HS Tariff Code: 2934.99.9001
• Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
• Stock Solution Storage: 0-4 °C for short term (days to weeks), or -20 °C for long term (months).