Carbomer 940

• CAS: 9003-01-4
• Catalog Number: ACM9003014-16
• Category: Other Products
• Molecular Weight: 0
• Molecular Formula: C₃H₄O₂
• Description: Polyvinyl carboxy polymer crosslinked with ethers of pentaerythritol. Used as a viscosity enhancer or gelling agent primarily in systems where clarity or viscosity is required. Viscosity: 45,000-70,000 cps (0.5% solution).
• Synonyms: 0mw);acrylicacid,polymers;acrylicacidhomopolymer;acrylicacidresin;Acrylicresin;acrysola1;acrysola3;acrysola5
• Boiling Point: 116°C
• Flash Point: 100°C
• Density: 1.2g/mL at 25°C
• Solubility: Water-soluble
• Appearance: Fine white powder
• Application: Gel-creams, hair gels, and other gels, lotions, creams.
• Storage: Store in a closed container at a dry place at room temperature
• Composition: Carbomer 940
• Features And Benefits: Acts as powerful, ph-sensitive gelling thickener useful for making clear gelsStabilizes emulsions
• Hazard Statements: C,T,Xi
• HS Code: 2916110000
• Safety Description: 53-45-36-27-26
• Supplemental Hazard Statements: H340-H350
• Symbol: GHS08

Case Study

Application of Carbomer 940 in the Fabrication of Mucoadhesive Oral Films for Periplaneta Americana Extract Delivery

Liu Y, et al. Journal of Drug Delivery Science and Technology, 2024, 101(A), 106199.

Carbomer 940 was experimentally employed as a key bioadhesive polymer in the formulation of a mucoadhesive oral film designed to enhance the therapeutic efficacy of Periplaneta Americana extract (PAE) for oral ulcer treatment. Utilizing the solvent casting method, PAE was first dissolved with hydroxypropyl-β-cyclodextrin in water, followed by sequential incorporation of sweetener (sucralose), low-substituted hydroxypropyl cellulose (L-HPC), Carbomer 940P, and poly(vinyl alcohol) (PVA-217). Each component was added after ensuring complete hydration and swelling of the previous one. PEG-400 was introduced post-cooling as a plasticizer. The resulting homogeneous solution was cast using a film applicator and dried at 60 °C for 3 hours.
Carbomer 940 functioned as a critical rheology modifier and mucoadhesive agent, significantly contributing to the film's elongation at break (548.86%) and adhesion force (2.34 N/cm²). The mucoadhesion time extended to nearly 90 minutes, enabling prolonged retention in the oral cavity. In vivo studies confirmed superior ulcer healing in rats administered with the Carbomer 940-based film containing 20% PAE.

Custom Q&A

What is Carbomer 940?

Carbomer 940 is a polyvinyl carboxy polymer used as a viscosity enhancer, gelling agent, or suspension agent.

What is Carbomer 940 used for?

Carbomer 940 is used primarily in systems where clarity or viscosity is required, such as in gel-creams, hair gels, lotions, and creams.

What is the typical use level of Carbomer 940?

The typical use level of Carbomer 940 is 0.1-0.5%, depending on the desired viscosity of the formulation.

How is Carbomer 940 neutralized?

Carbomer 940 can be neutralized with inorganic bases such as NaOH or KOH, triethanolamine (TEA), Tetrasodium EDTA, or Suttocide A.

What is the pH range required to achieve gel structure with Carbomer 940?

The pH needs to be raised to >6.0 to achieve a gel structure with Carbomer 940.

What are the benefits of Carbomer 940?

Carbomer 940 acts as a powerful, pH-sensitive gelling thickener that is useful for making clear gels and stabilizing emulsions.

How does Carbomer 940 compare to standard surfactant thickeners in terms of fragrance and essential oil incorporation?

Carbomer 940 has better viscosity and can withstand the incorporation of different fragrance and essential oils compared to standard surfactant thickeners.

Can Carbomer 940 suspend heavy particles?

Yes, Carbomer 940 is excellent at suspending heavy particles and can create a network that effectively traps and suspends beads.

What is the recommended neutralizing agent for Carbomer 940?

Tetrasodium EDTA or Suttocide A are recommended as neutralizing agents for Carbomer 940.

How should Carbomer 940 be added to formulations?

Carbomer 940 should be added to room temperature liquid only.