Calcium laurate

• CAS: 4696-56-4
• Catalog Number: ACM4696564
• Category: Main Products
• Molecular Weight: 438.7
• Molecular Formula: C24H46CaO4
• Melting Point: 182°C
• Flash Point: 134.1°C
• Assay: 0.98
• Packaging: 1 kg

Case Study

Study on the effect of pH on the bactericidal activity of calcium laurate

Morikawa, Toshiya, Yoshiaki Yamamoto, and Yoshimune Nonomura. Journal of Oleo Science 67.7 (2018): 859-862.

Calcium salts of fatty acids are high melting point powders with excellent lubricity and water repellency and are often used as raw materials for cosmetics. Several calcium salts of fatty acids, such as calcium laurate, have highly selective bactericidal activity against Staphylococcus aureus and Propionibacterium acnes and low bactericidal activity against Staphylococcus epidermidis. The effect of pH on the bactericidal behavior of calcium laurate was evaluated and it was shown that under acidic conditions, it showed high bactericidal activity against both bacteria, but the selectivity became lower. This finding can be used to design shower gels and cosmetics containing lauric acid.
The bactericidal activity of calcium laurate against Staphylococcus aureus, Staphylococcus epidermidis, and Propionibacterium acnes was evaluated. 50 μL of fungal solution, 100 mg of calcium laurate, and 50 μL of 2wt ethanol solution were added to 10 mL of sterile 50 mM phosphate-citrate buffer (pH 5.0, 6.0, or 7.0) and suspended. The bacterial concentration in this suspension was 5.50.2 log colony forming units (CFU) mL. The resulting reaction solution was spread on SCDLP agar plates. The bacterial counts were evaluated after 1, 3, and 24 h.

Calcium laurate for the preparation of spherical CaO particles

Hu, Yingchao, Hongyuan Lu, and Hailong Li. Chemical Engineering Journal 404 (2021): 127137.

A facile agar-assisted molding technique for the granulation of CaO adsorbents is proposed, inspired by the strong coagulation and hydrophobicity of agar powder. Finding effective calcium precursors to produce CaO adsorbents is also crucial for their CO2 adsorption performance. Therefore, two novel organometallic precursors, namely calcium laurate and calcium myristate, were used in the current work. The obtained CaO adsorbents exhibited a high degree of sphericity and uniform size of 3-4 mm. In addition, these adsorbent particles exhibited good CO2 adsorption performance. In particular, the particles using calcium laurate as a precursor showed impressive performance, including high adsorption rate and carbonation conversion. The outstanding performance is attributed to the rich porosity and porous structure of this adsorbent.
Calcium laurate and calcium myristate were calcined at 850 °C for 1 h in air to obtain calcium oxide powder. Then, the powders were further granulated by an agar-assisted molding method. The obtained CaO powder after calcination of calcium precursor was mixed with agar powder in a mass ratio of 5:1. A certain amount of deionized water was then added to the powder mixture. Next, the mixture was heated to 150 °C while being kept at this temperature with stirring until the agar powder was dissolved. The formed hot slurry was dripped into cold methyl silicone oil through a dropper and the droplets were left standing in the oil for 12 hours to solidify. After that, the solidified particles were washed with petroleum ether. The washed adsorbent particles were further dried in a vacuum oven at 60 °C for 2 hours and the final spherical CaO particles were obtained after calcination in air at 800 °C in a muffle furnace for half an hour.

Study on the biofilm production behavior of Pseudomonas aeruginosa in calcium laurate metal fatty acid salt medium

Abinaya Sindu, P., and Pennathur Gautam. Canadian journal of microbiology 63.1 (2017): 61-73.

Pseudomonas aeruginosa is a ubiquitous organism that thrives in harsh conditions and is resistant to metal fatty acid salt (MFAS) ions. This study proves the concept of using this organism for biodegradation of MFAS such as calcium laurate. Effects of MFAS on the growth of planktonic forms and biofilm formation of Pseudomonas aeruginosa. When used as the sole carbon source, biofilm formation was higher in the presence of all MFAS, although less biofilm was formed in the presence of cadmium and copper. There was no effect on the planktonic form of the organism, but biofilm formation was increased in the presence of magnesium palmitate. This study suggests that metal ions play a key role in biofilm formation. HPLC analysis showed that hexoses were the major components of biofilm polysaccharides compared to pentoses. The structure of biofilm polysaccharides and the coordination of metal ions to biofilm polysaccharides were confirmed by FTIR and Raman spectroscopy.
Pseudomonas aeruginosa MTCC 2297 strain was grown in minimal mineral medium M9 supplemented with 1.0 % (w/v) calcium laurate as a carbon source. The pH of the medium was adjusted to 7 with 1 M NaOH. The medium (50 ml) was dispensed into 250 ml conical flasks, sterilized and inoculated with an overnight culture grown in the same medium and incubated at 37 degrees Celsius on a rotator. Samples were removed every 1 hour. All samples were filtered using filter paper with a pore size of 20-25 μm to remove residual salts.

Effect of calcium laurate on growth performance in chickens

Rebucci, R., et al. Book of abstract: Italian Journal of Animal Science. Taylor & Francis, 2021. 142-142.

Reducing the use of antibiotics is one of the biggest challenges facing animal production. Many alternative substances to antibiotics have been studied by the scientific community, including medium-chain fatty acids, due to their antimicrobial and protective effects on intestinal health. The mode of administration represents a critical point, as free fatty acids are dissociated in the stomach and partially adsorbed and metabolized in the proximal gastrointestinal tract, reducing their impact along the distal intestine. The study investigated the effects of calcium laurate saponified on growth performance and intestinal antioxidant status in broiler chicks.
A total of 720 female chicks were assigned to one of three dietary treatments: CTR (basal diet alone), T1 (basal diet and lauric acid, 1 g/kg), and T2 (basal diet and calcium laurate saponified (C12-Ca), 1 g/kg), considering the basal diet during the nursery period (0-11 d), the growing period (12-21 d), and the finishing period (22-42 d). Body weight (BW), average daily gain (ADG), and average daily feed intake (ADFI) were measured, and feed conversion ratio (FCR) was calculated. The chicks were slaughtered at 42 days, and intestinal samples were collected by scraping the duodenal mucosa using sterile glass microscope slides to investigate the effects of C12-Ca soap on intestinal antioxidant status (superoxide dismutase SOD, catalase CAT, and total antioxidant capacity TAOC). Compared with lauric acid, C12-Ca significantly improved (p < .05) FCR in the initial period (0-11 days), while no differences were found in BW, ADG, and ADFI. Intestinal levels of SOD and CAT activities were significantly increased in C12-CA-treated chicks (p < .05). The results of this study suggest that C12-Ca may not be completely dissociated in the stomach and modulate intestinal antioxidant status.

Custom Q&A

What is the molecular formula of Calcium laurate?

The molecular formula of Calcium laurate is C24H46CaO4.

What is the molecular weight of Calcium laurate?

The molecular weight of Calcium laurate is 438.7 g/mol.

What are some synonyms for Calcium laurate?

Some synonyms for Calcium laurate are Calcium dodecanoate, Calcium dilaurate, and Dodecanoic acid, calcium salt.

What are the component compounds of Calcium laurate?

The component compounds of Calcium laurate are Calcium and Lauric Acid.

What is the IUPAC name of Calcium laurate?

The IUPAC name of Calcium laurate is calcium;dodecanoate.

What is the InChIKey of Calcium laurate?

The InChIKey of Calcium laurate is HIAAVKYLDRCDFQ-UHFFFAOYSA-L.

What is the CAS number of Calcium laurate?

The CAS number of Calcium laurate is 4696-56-4.

How many hydrogen bond acceptor counts does Calcium laurate have?

Calcium laurate has 4 hydrogen bond acceptor counts.

What is the topological polar surface area of Calcium laurate?

The topological polar surface area of Calcium laurate is 80.3 Å2.

Is the compound is canonicalized for Calcium laurate?

Yes, the compound is canonicalized for Calcium laurate.