Boronic acid,b-[4-(1-piperidinylsulfonyl)phenyl]-

• CAS: 486422-58-6
• Catalog Number: ACM486422586
• Category: Other Products
• Molecular Weight: 269.13
• Molecular Formula: C₁₁H₁₆BNO₄S
• Synonyms: 486422-58-6, 4-(PIPERIDIN-1-YLSULFONYL)PHENYLBORONIC ACID, 1-(4-Boronophenylsulfonyl)Piperidine, AG-F-64521, 4-(Piperidin-1-ylsulphonyl)benzeneboronic acid, 4-(N-Piperidinylsulphonamido)benzeneboronic acid, ACMC-209kdm, SureCN1742543, CTK4J0922, MolPort-001-768-778, AC1Q7157, ANW-30680, OR4101, AKOS015854063, AB26470, AK-85452, AM806846, KB-35147, 4-(piperidine-1-sulfonyl)phenylboronic acid, (4-piperidin-1-ylsulfonylphenyl)boronic acid
• IUPAC Name: (4-piperidin-1-ylsulfonylphenyl)boronic acid
• Canonical SMILES: B(C1=CC=C(C=C1)S(=O)(=O)N2CCCCC2)(O)O
• InChI Key: MIEADZYHESCCES-UHFFFAOYSA-N
• Boiling Point: 471.2ºC at 760mmHg
• Melting Point: 268-272ºC
• Flash Point: 238.8ºC
• Density: 1.37g/cm³
• Exact Mass: 269.08900
• Hazard Statements: Xi
• H-Bond Acceptor: 5
• H-Bond Donor: 2

Synthetic Use

Downstream Synthesis Route 1

• 486422-58-6
• 872620-93-4

• 872673-99-9

Reference: [1]Current Patent Assignee: ASTRAZENECA PLC - WO2006/1754, 2006, A1
Location in patent: Page/Page column 35

Downstream Synthesis Route 2

• 849519-42-2
• 486422-58-6
• 76-05-1

• 1001330-86-4

Reference: [1]Location in patent: experimental part
Covel, Jonathan A.; Santora, Vincent J.; Smith, Jeffrey M.; Hayashi, Rena; Gallardo, Charlemagne; Weinhouse, Michael I.; Ibarra, Jason B.; Schultz, Jeffrey A.; Park, Douglas M.; Estrada, Scott A.; Hofilena, Brian J.; Pulley, Michelle D.; Smith, Brian M.; Ren, Albert; Suarez, Marissa; Frazer, John; Edwards, Jeffrey; Hauser, Erin K.; Lorea, Jodie; Semple, Graeme; Grottick, Andrew J.
[Journal of Medicinal Chemistry, 2009, vol. 52, # 18, p. 5603 - 5611]

* For details of the synthesis route, please refer to the original source to ensure accuracy.