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Structure

Bohemine

CAS
189232-42-6
Catalog Number
ACM189232426
Category
Inhibitors
Molecular Weight
340.42
Molecular Formula
C18H24N6O
MSDS COA Spec Sheet

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Specification

Description
Bohemine is a purine analogue and is a synthetic and selective CDK inhibitor with IC50s of 4.6 μM, 83 μM, and 2.7 μM for Cdk2/cyclin E, Cdk2/cyclin A, and Cdk9/cyclin T1, respectively. Bohemine also inhibits ERK2 with an IC50 of 52 μM and has less inhibitory effect on CDK1, CDK4 and CDK6. Bohemine has a broad spectrum anti-cancer activities.
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