Structure

Boc-Asp(OBzl)-OH

CAS
7536-58-5
Catalog Number
ACM7536585
Category
Amino Acids
Molecular Weight
323.34

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Specification

Description
Building block for introduction of aspartic acid amino-acid residues by Boc SPPS.
Synonyms
Boc-Asp(OBzl)-OH, N-α-t.-Boc-L-aspartic acid β-benzyl ester
InChI
1S/C16H21NO6/c1-16(2,3)23-15(21)17-12(14(19)20)9-13(18)22-10-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,17,21)(H,19,20)
InChI Key
SOHLZANWVLCPHK-UHFFFAOYSA-N
Application
Peptide synthesis.
Assay
≥98% (TLC)
Form
powder
Functional Group
carboxylic acid
MDL Number
MFCD00065564
Quality Level
200
Reaction Suitability
reaction type: Boc solid-phase peptide synthesis
Storage Temperature
2-30℃

Upstream Synthesis Route 1

  • 24424-99-5
  • 2177-63-1
  • 7536-58-5

Reference: [1] Patent: CN106866502, 2017, A, . Location in patent: Paragraph 0230-0234

Upstream Synthesis Route 2

  • 18595-34-1
  • 2177-63-1
  • 7536-58-5

Reference: [1]Justus Liebigs Annalen der Chemie,1968,vol. 716,p. 175 - 185

Downstream Synthesis Route 1

  • 7536-58-5
  • 13726-67-5

Reference: [1] Tetrahedron Letters, 2002, vol. 43, # 2, p. 311 - 313

Downstream Synthesis Route 2

  • 7536-58-5
  • 2177-63-1

Reference: [1] Journal of the American Chemical Society, 1995, vol. 117, # 17, p. 4729 - 4741
[2] Tetrahedron, 2016, vol. 72, # 13, p. 1706 - 1715

Downstream Synthesis Route 3

  • 7536-58-5
  • 13726-67-5

Reference: [1]Tetrahedron Letters,2002,vol. 43,p. 311 - 313

Downstream Synthesis Route 4

  • 21715-90-2
  • 7536-58-5
  • 66851-88-5

Reference: [1]Current Patent Assignee: FEDERAL STATE UNITARY ENTERPRISE OF RUSSIAN FEDERATION - EP2397488, 2019, B1
Location in patent: Paragraph 0171; 0172

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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