Boc-(2S,3S)-3-hydroxypyrrolidine-2-carboxylic acid

CAS

187039-57-2

Catalog Number

ACM187039572-1

Category

Amino Acids

Molecular Weight

231.2

Molecular Formula

C10H17NO5

MSDS COA Spec Sheet

If you have any other questions or need other size, please get a quote.

Specification

Description

(2S,3S)-1-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine-2-carboxylic acid is a chiral, α-amino acid that is used extensively in organic synthesis due to its intriguing physical and chemical properties. The compound is also known as Boc-D-3-hydroxyproline, Boc-D-Hyp-OH or D-3-Hyp.

Synonyms

(2S,3S)-3-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid

IUPAC Name

(2S,3S)-3-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid

Canonical SMILES

CC(C)(C)OC(=O)N1CCC(C1C(=O)O)O

InChI

1S/C10H17NO5/c1-10(2,3)16-9(15)11-5-4-6(12)7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)/t6-,7-/m0/s1

InChI Key

JLDHXHPQMBNKMC-BQBZGAKWSA-N

Boiling Point

390.9±42.0 ℃at 760 mmHg

Flash Point

190.2±27.9 ℃

Density

1.3±0.1 g/cm³

Application

The compound can be used for developing novel drug candidates, as a chiral building block in the synthesis of biologically active compounds, and as proline isomers in peptide chemistry and protein applications. Studies also show that it can inhibit the activity of protease enzymes and is used in peptide synthesis.

Exact Mass

231.110672

Functional Group

Boc

HS Code

2933990090

LogP

-0.54

MDL Number

MFCD04974546

PSA

87.07