8-Hydroxyquinaldine

• CAS: 826-81-3
• Catalog Number: ACM826813
• Category: Other Products
• Molecular Weight: 159.18g/mol
• Molecular Formula: C10H9NO
• IUPAC Name: 2-methylquinolin-8-ol
• Canonical SMILES: CC1=NC2=C(C=CC=C2O)C=C1
• InChI: InChI=1S/C10H9NO/c1-7-5-6-8-3-2-4-9(12)10(8)11-7/h2-6,12H,1H3
• InChI Key: NBYLBWHHTUWMER-UHFFFAOYSA-N
• Boiling Point: 267.0 °C
• Melting Point: 73.8 °C
• Complexity: 160
• Covalently-Bonded Unit Count: 1
• EC Number: 212-562-6
• Exact Mass: 159.068414g/mol
• Formal Charge: 0
• H-Bond Acceptor: 2
• H-Bond Donor: 1
• Heavy Atom Count: 12
• LogP: 2.33 (LogP)
• Monoisotopic Mass: 159.068414g/mol
• NSC Number: 58553
• Rotatable Bond Count: 0
• UNII: 7W631H5302
• XLogP3: 2.3

Synthetic Use

Upstream Synthesis Route 1

• 18826-95-4
• 95-55-6

• 826-81-3
• 3846-73-9

Reference: [1] Russian Journal of General Chemistry, 2016, vol. 86, # 7, p. 1613 - 1618[2] Zh. Obshch. Khim., 2016, vol. 86, # 7, p. 1135 - 1140,6

Downstream Synthesis Route 1

• 123-91-1
• 826-81-3

• 14510-06-6

Reference: [1] Patent: US2009/54482, 2009, A1,

Downstream Synthesis Route 2

• 826-81-3

• 14510-06-6

Reference: [1] RSC Advances, 2015, vol. 5, # 129, p. 107012 - 107019

Downstream Synthesis Route 3

• 826-81-3
• 108-24-7

• 27037-61-2

Reference: [1]Albrecht, Markus; Blau, Oliver; Witt, Karen; Wegelius, Elina; Nissinen, Maija; Rissanen, Kari; Froehlich, Roland
[Synthesis, 1999, # 10, p. 1819 - 1829]

Downstream Synthesis Route 4

• 826-81-3
• 100-39-0

• 93315-49-2

Reference: [1]Current Patent Assignee: GUANGDONG UNIVERSITY OF TECHNOLOGY; UNIV DE PARIS VII - CN110041309, 2019, A
Location in patent: Paragraph 0077-0080

Downstream Synthesis Route 5

• 826-81-3
• 75-36-5

• 26872-39-9

Reference: [1]Current Patent Assignee: ONXEO - EP2147912, 2010, A1
Location in patent: Page/Page column 9; 10; 11
[2]Current Patent Assignee: Novartis (w/o Sandoz); NOVARTIS AG - US2875126, 1956, A

* For details of the synthesis route, please refer to the original source to ensure accuracy.