6-(Methylsulfonyl)pyridine-3-boronic acid

• CAS: 1088496-41-6
• Catalog Number: ACM1088496416
• Category: Other Products
• Molecular Weight: 201.03
• Molecular Formula: C₆H₈BNO₄S
• Synonyms: 1088496-41-6, 2-(METHYLSULFONYL)PYRIDINE-5-BORONIC ACID, (6-(Methylsulfonyl)pyridin-3-yl)boronic acid, SureCN2370450, ACMC-20991i, CTK4A6214, MolPort-015-143-330, ANW-15988, AKOS015852526, AG-L-20299, PB33138, AK-91858, BD230031, KB-15747, 2-(Methylsulfonyl)pyridine-5-boronic acid,, Y6601, A-4901, 6-(METHYLSULFONYL)PYRIDINE-3-BORONIC ACID, (6-METHANESULFONYLPYRIDIN-3-YL)BORONIC ACID, I02-3360
• IUPAC Name: (6-methylsulfonylpyridin-3-yl)boronic acid
• Canonical SMILES: B(C1=CN=C(C=C1)S(=O)(=O)C)(O)O
• InChI Key: OBWIRUCBMIYFBP-UHFFFAOYSA-N
• Boiling Point: 487.373ºC at 760 mmHg
• Flash Point: 248.555ºC
• Density: 1.477 g/cm³
• Exact Mass: 201.02700
• H-Bond Acceptor: 5
• H-Bond Donor: 2

Synthetic Use

Downstream Synthesis Route 1

• 477251-96-0
• 1088496-41-6

• 477252-35-0

Reference: [1]Location in patent: scheme or table
Guay, Daniel; Boulet, Louise; Friesen, Richard W.; Girard, Mario; Hamel, Pierre; Huang, Zheng; Laliberte, France; Laliberte, Sebastien; Mancini, Joseph A.; Muise, Eric; Pon, Doug; Styhler, Angela
[Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 20, p. 5554 - 5558]

Downstream Synthesis Route 2

• 1088496-41-6
• 1401098-20-1

• 1401097-85-5

Reference: [1]Current Patent Assignee: PFIZER INC - WO2012/135570, 2012, A1
Location in patent: Page/Page column 115

Downstream Synthesis Route 3

• 1088496-41-6
• 1476713-22-0

• 1476713-40-2

Reference: [1]Younis, Yassir; Douelle, Frederic; González Cabrera, Diego; Le Manach, Claire; Nchinda, Aloysius T.; Paquet, Tanya; Street, Leslie J.; White, Karen L.; Zabiulla, K. Mohammed; Joseph, Jayan T.; Bashyam, Sridevi; Waterson, David; Witty, Michael J.; Wittlin, Sergio; Charman, Susan A.; Chibale, Kelly
[Journal of Medicinal Chemistry, 2013, vol. 56, # 21, p. 8860 - 8871]

* For details of the synthesis route, please refer to the original source to ensure accuracy.