6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride

• CAS: 57196-62-0
• Catalog Number: ACM57196620
• Category: Other Products
• Molecular Weight: 199.67
• Molecular Formula: C₁₀H₁₄ClNO
• Synonyms: LS-85730, 6-Methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride, ISOQUINOLINE, 6-METHOXY-1,2,3,4-TETRAHYDRO-, HYDROCHLORIDE, 57196-62-0
• IUPAC Name: 6-methoxy-1,2,3,4-tetrahydroisoquinolin-2-ium chloride
• Canonical SMILES: COC1=CC2=C(CNCC2)C=C1.Cl
• InChI Key: QIUIKPQXMJJOQT-UHFFFAOYSA-N
• Boiling Point: 283.6ºC at 760 mmHg
• Melting Point: 230-232.5ºC
• Flash Point: 109.2ºC
• Exact Mass: 199.07600
• Hazard Statements: Xi: Irritant
• H-Bond Acceptor: 2
• H-Bond Donor: 1

Synthetic Use

Upstream Synthesis Route 1

• 942150-85-8

• 57196-62-0

Reference: [1] Organic Process Research and Development, 2007, vol. 11, # 3, p. 463 - 465
[2] Patent: US2008/33177, 2008, A1, . Location in patent: Page/Page column 9
[3] Journal of Medicinal Chemistry, 2013, vol. 56, # 8, p. 3414 - 3418

Upstream Synthesis Route 2

• 50-00-0
• 55-81-2

• 57196-62-0

Reference: [1] Patent: WO2003/99786, 2003, A2, . Location in patent: Page 35

Upstream Synthesis Route 3

• 14446-29-8

• 57196-62-0

Reference: [1]Journal of Chemical Research, Miniprint,1987,p. 501 - 526

Downstream Synthesis Route 1

• 57196-62-0

• 42923-77-3

Reference: [1] Journal of Medicinal Chemistry, 2013, vol. 56, # 8, p. 3414 - 3418

Downstream Synthesis Route 2

• 57196-62-0
• 107-13-1

• 793672-12-5

Reference: [1]Journal of medicinal chemistry,2004,vol. 47,p. 5451 - 5466

* For details of the synthesis route, please refer to the original source to ensure accuracy.