5-Phenyloxazole-4-carboxylic acid

• CAS: 99924-18-2
• Catalog Number: ACM99924182
• Category: Other Products
• Molecular Weight: 189.17
• Molecular Formula: C₁₀H₇NO₃
• Synonyms: BUTTPARK 153\57-35;5-PHENYL-OXAZOLE-4-CARBOXYLIC ACID;5-PHENYL-1,3-OXAZOLE-4-CARBOXYLIC ACID;5-Phenyl-1,3-oxazole-4-carboxylic acid ,97%
• IUPAC Name: 5-phenyl-1,3-oxazole-4-carboxylic acid
• Canonical SMILES: C1=CC=C(C=C1)C2=C(N=CO2)C(=O)O
• InChI Key: RUKDIKJSGDVSIF-UHFFFAOYSA-N
• Boiling Point: 354.73ºC at 760 mmHg
• Melting Point: 181ºC
• Density: 1.32 g/cm³
• Exact Mass: 189.04300
• Hazard Statements: Xi:Irritant
• H-Bond Acceptor: 4
• H-Bond Donor: 1
• Safety Description: S26-S37/39

Synthetic Use

Upstream Synthesis Route 1

• 32998-97-3

• 99924-18-2

Reference: [1] The Journal of organic chemistry, 2002, vol. 67, # 11, p. 3601 - 3606

Upstream Synthesis Route 2

• 38061-18-6

• 99924-18-2

Reference: [1] Journal of Medicinal Chemistry, 1986, vol. 29, # 3, p. 333 - 341

Downstream Synthesis Route 1

• 99924-18-2

• 337508-64-2

Reference: [1]Couture, Axel; Grandclaudon, Pierre; Hoarau, Christophe; Cornet, Josephine; Henichart, Jean-Pierre; Houssin, Raymond
[Journal of Organic Chemistry, 2002, vol. 67, # 11, p. 3601 - 3606]
[2]Current Patent Assignee: JOHNSON & JOHNSON INC - WO2010/143158, 2010, A1
Location in patent: Page/Page column 67-68
[3]Current Patent Assignee: JOHNSON & JOHNSON INC - US2012/115916, 2012, A1
Location in patent: Page/Page column 27

* For details of the synthesis route, please refer to the original source to ensure accuracy.