4-CHLORO-8-METHYLQUINAZOLINE

• CAS: 58421-80-0
• Catalog Number: ACM58421800
• Category: Other Products
• Molecular Weight: 178.61
• Molecular Formula: C9H7ClN2
• Synonyms: 4-Chloro-8-methylquinazoline, 58421-80-0, SBB054654, AGN-PC-01RHFA, CTK5A8284, 4-chloranyl-8-methyl-quinazoline, Quinazoline, 4-chloro-8-methyl-, ANW-32942, ZINC40448078, 4-CHLORO-8-METHYL-QUINAZOLINE, AKOS012384449, AG-G-06677, AK130673, KB-38164, EN300-67878, A831875
• IUPAC Name: 4-chloro-8-methylquinazoline
• Canonical SMILES: CC1=CC=CC2=C1N=CN=C2Cl
• InChI Key: UTBDPFFXKANFFT-UHFFFAOYSA-N
• Boiling Point: 298.2ºC at 760 mmHg
• Flash Point: 162.3ºC
• Density: 1.292g/cm³
• Exact Mass: 178.03000
• H-Bond Acceptor: 2
• H-Bond Donor: 0

Synthetic Use

Upstream Synthesis Route 1

• 19181-54-5

• 58421-80-0

Reference: [1] Patent: WO2017/106607, 2017, A1, . Location in patent: Paragraph 00224

Upstream Synthesis Route 2

• 4389-45-1

• 58421-80-0

Reference: [1] Bioorganic and Medicinal Chemistry, 1996, vol. 4, # 8, p. 1203 - 1207
[2] Patent: WO2013/96194, 2013, A1,
[3] European Journal of Medicinal Chemistry, 2013, vol. 63, p. 662 - 669
[4] Medicinal Chemistry Research, 2014, vol. 23, # 5, p. 2584 - 2595
[5] Patent: WO2017/106607, 2017, A1,

Upstream Synthesis Route 3

• 19181-54-5

• 58421-80-0

Reference: [1]Patent: WO2017/106607,2017,A1 .Location in patent: Paragraph 00224

Downstream Synthesis Route 1

• 58421-80-0

• 19181-54-5

Reference: [1] Chemische Berichte, 1905, vol. 38, p. 3561

Downstream Synthesis Route 2

• 58421-80-0

• 19181-54-5

Reference: [1]Chemische Berichte,1905,vol. 38,p. 3561

* For details of the synthesis route, please refer to the original source to ensure accuracy.