4-(4-FLUOROPHENYL)-1,3-THIAZOL-2-AMINE

• CAS: 77815-14-6
• Catalog Number: ACM77815146
• Category: Other Products
• Molecular Weight: 194.23
• Molecular Formula: C9H7FN2S
• Synonyms: Oprea1_850524, MLS000707841, ALBB-000310, ZINC00126157, 4-(4-fluorophenyl)-1,3-thiazol-2-amine, 4-(4-Fluoro-phenyl)-thiazol-2-ylamine, Thiazole, 2-amino-4-(4-fluorophenyl)-, BAS 07340861, SMR000288908, AB-601/30964014, A2521/0107136, 77815-14-6
• IUPAC Name: 4-(4-fluorophenyl)-1,3-thiazol-2-amine
• Canonical SMILES: C1=CC(=CC=C1C2=CSC(=N2)N)F
• InChI Key: WSOKJBHBMAGBIP-UHFFFAOYSA-N
• Boiling Point: 359.1ºC at 760 mmHg
• Melting Point: 102-110ºC
• Flash Point: 171ºC
• Density: 1.349g/cm³
• Exact Mass: 194.03100
• Hazard Statements: Xi: Irritant
• H-Bond Acceptor: 3
• H-Bond Donor: 1
• Safety Description: 26-36/37/39

Synthetic Use

Upstream Synthesis Route 1

• 403-42-9
• 17356-08-0

• 77815-14-6

Reference: [1]Kakati, Praachi; Singh, Preeti; Yadav, Priyanka; Awasthi, Satish Kumar
[New Journal of Chemistry, 2021, vol. 45, # 15, p. 6724 - 6738]

Upstream Synthesis Route 2

• 17356-08-0
• 456-04-2

• 77815-14-6

Reference: [1]Khillare, Lalit D.; Pratap, Umesh R.; Bhosle, Manisha R.; Dhumal, Sambhaji T.; Bhalerao, Mahendra B.; Mane, Ramrao A.
[Research on Chemical Intermediates, 2017, vol. 43, # 8, p. 4327 - 4337]
[2]Walchshofer; Minjat; Tinland; et al.
[European Journal of Medicinal Chemistry, 1986, vol. 21, # 1, p. 59 - 64]

Downstream Synthesis Route 1

• 395-44-8
• 77815-14-6

• 1048643-71-5

Reference: [1]Patent: WO2008/101029,2008,A2 .Location in patent: Page/Page column 83; 84

* For details of the synthesis route, please refer to the original source to ensure accuracy.