3,4-Dihydroxy-3-cyclobutene-1,2-dione

• CAS: 2892-51-5
• Catalog Number: ACM2892515-1
• Category: Organic & Printed Electronics
• Molecular Weight: 114.06
• Molecular Formula: (HO)2C4(=O)2
• Description: 3,4-dihydroxy-3-cyclobutene-1,2 dione, commonly known as squaric acid, is widely used in bioorganic and medicinal chemistry. It is an inhibitor of glyoxylase, semiqauric acid, pyruvate dehrogenase, and transketolase. It is used as a replacement for phosphate in a peptide-based ligand for an SH2 domain. Its derivatives are high-affinity ligands for excitatory amino acid receptors. These derivatives are also used as dyes for fluorescence detection of small biological molecules.
• Synonyms: Squaric acid
• IUPAC Name: 3,4-Dihydroxycyclobut-3-ene-1,2-dione
• Canonical SMILES: C1(=C(C(=O)C1=O)O)O
• InChI: InChI=1S/C4H₂O4/c5-1-2(6)4(8)3(1)7/h5-6H
• InChI Key: PWEBUXCTKOWPCW-UHFFFAOYSA-N
• Boiling Point: 250.96 °C
• Melting Point: >300 °C
• Flash Point: 190 °C
• Density: 1.82 g/cm³
• Solubility: Soluble in water
• Appearance: Gray crystalline solid
• Application: 3,4-Dihydroxy-3-cyclobutene-1,2-dione can be used:; In fluorescence detection in immunoassays, hybridization assays, enzymatic reactions, and other analytical procedures.; To form diffraction quality crystals.; To synthesize a squarate dianion, which is used as a building block to create uncharged polymeric networks. These ordered structures are used in catalysis, nonlinear optics, electrical conductivity, molecular recognition, and molecular sieves.
• Storage: Inert atmosphere,Room Temperature
• Assay: ≥99.0% (HPLC)
• Complexity: 178
• Covalently-Bonded Unit Count: 1
• EC Number: 220-761-4
• Exact Mass: 113.99530854
• Features And Benefits: 1. High quality products; 2. Fast delivery; 3. Additional products can be ordered, please contact us for details
• Formal Charge: 0
• H-Bond Acceptor: 4
• H-Bond Donor: 2
• Heavy Atom Count: 8
• MDL Number: MFCD00001334
• Monoisotopic Mass: 113.99530854
• NACRES: NA.23
• NSC Number: 624671;125692
• Packaging: Packaging; 5 g in glass bottle; 25, 100 g in poly bottle
• PubChem ID: 24847567
• Quality Level: 200
• Rotatable Bond Count: 0
• Topological Polar Surface Area: 74.6 Ų
• UNII: SVR9D0VODW
• XLogP3: -0.7

Custom Q&A

What is the molecular weight of 3,4-Dihydroxy-3-cyclobutene-1,2-dione?

The molecular weight of 3,4-Dihydroxy-3-cyclobutene-1,2-dione is 114.06.

What is the SMILES notation for 3,4-Dihydroxy-3-cyclobutene-1,2-dione?

The SMILES notation for 3,4-Dihydroxy-3-cyclobutene-1,2-dione is C1(=C(C(=O)C1=O)O)O.

What is the InChIKey for 3,4-Dihydroxy-3-cyclobutene-1,2-dione?

The InChIKey for 3,4-Dihydroxy-3-cyclobutene-1,2-dione is PWEBUXCTKOWPCW-UHFFFAOYSA-N.

What is the boiling point of 3,4-Dihydroxy-3-cyclobutene-1,2-dione?

The boiling point of 3,4-Dihydroxy-3-cyclobutene-1,2-dione is 250.96 °C.

In what category does 3,4-Dihydroxy-3-cyclobutene-1,2-dione fall under?

3,4-Dihydroxy-3-cyclobutene-1,2-dione falls under CHO Containing Functional Groups.

How is 3,4-Dihydroxy-3-cyclobutene-1,2-dione used as a replacement for phosphate?

It is used as a replacement for phosphate in a peptide-based ligand for an SH2 domain.

What is the solubility of 3,4-Dihydroxy-3-cyclobutene-1,2-dione?

3,4-Dihydroxy-3-cyclobutene-1,2-dione is soluble in water.

How is 3,4-Dihydroxy-3-cyclobutene-1,2-dione used in analytical procedures?

It can be used in fluorescence detection in immunoassays, hybridization assays, enzymatic reactions, and other analytical procedures.

Why is 3,4-Dihydroxy-3-cyclobutene-1,2-dione used to synthesize squarate dianion?

It is used to synthesize a squarate dianion, which is a building block to create uncharged polymeric networks for various applications.

What are some of the features and benefits of 3,4-Dihydroxy-3-cyclobutene-1,2-dione?

Some of the features and benefits include high quality products, fast delivery, and the option to order additional products.