(2R,3R)-(-)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol

• CAS: 32305-98-9
• Catalog Number: ACM32305989
• Category: Other Products
• Molecular Weight: 498.543g/mol
• Molecular Formula: C31H32O2P2
• Synonyms: UNII-ESK57W53CI; MFCD00014107; ST24033353; (-)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane, 98%; (4R,5R)-4,5-Bis(diphenylphosphino-methyl)-2,2-dimethyl-1,3-dioxolane; (4R,5R)-(-)-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane; SC11345; (((4R,5R)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene))bis(diphenylphosphine); KS-000013U5; NSC699410
• IUPAC Name: [(4R,5R)-5-(diphenylphosphanylmethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl-diphenylphosphane
• Canonical SMILES: CC1(OC(C(O1)CP(C2=CC=CC=C2)C3=CC=CC=C3)CP(C4=CC=CC=C4)C5=CC=CC=C5)C
• InChI: InChI=1S/C31H32O2P2/c1-31(2)32-29(23-34(25-15-7-3-8-16-25)26-17-9-4-10-18-26)30(33-31)24-35(27-19-11-5-12-20-27)28-21-13-6-14-22-28/h3-22,29-30H,23-24H2,1-2H3/t29-,30-/m0/s1
• InChI Key: VCHDBLPQYJAQSQ-KYJUHHDHSA-N
• Storage: 0-6°C
• Complexity: 528
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 2
• EC Number: 250-984-2
• Exact Mass: 498.188g/mol
• H-Bond Acceptor: 2
• Heavy Atom Count: 35
• Monoisotopic Mass: 498.188g/mol
• NSC Number: 699410
• Rotatable Bond Count: 8
• Topological Polar Surface Area: 18.5A^2
• UNII: ESK57W53CI

Synthetic Use

Upstream Synthesis Route 1

• 99436-45-0

• 32305-98-9

Reference: [1] Bulletin des Societes Chimiques Belges, 1991, vol. 100, # 3, p. 247 - 257

Upstream Synthesis Route 2

• 4376-01-6
• 37002-45-2

• 32305-98-9

Reference: [1] Patent: US2010/234642, 2010, A1, . Location in patent: Page/Page column 13

Upstream Synthesis Route 3

• 50622-09-8

• 32305-98-9

Reference: [1] Tetrahedron Letters, 1993, vol. 34, # 28, p. 4523 - 4526
[2] Journal of Organic Chemistry, 1980, vol. 45, # 15, p. 2995 - 2999
[3] Bulletin des Societes Chimiques Belges, 1991, vol. 100, # 3, p. 247 - 257

Upstream Synthesis Route 4

• 94665-48-2

• 32305-98-9

Reference: [1]Brunner, H.; Zettlmeier, W.
[Bulletin des Societes Chimiques Belges, 1991, vol. 100, # 3, p. 247 - 257]

Downstream Synthesis Route 1

• 32305-98-9

• 94665-48-2

Reference: [1]Sugiura, Masaharu; Sato, Norimasa; Sonoda, Yuko; Kotani, Shunsuke; Nakajima, Makoto
[Chemistry - An Asian Journal, 2010, vol. 5, # 3, p. 478 - 481]
[2]Bianchet, Stephen; Potvin, Pierre G.
[Canadian Journal of Chemistry, 1992, vol. 70, # 8, p. 2256 - 2265]
[3]Yamamoto, Keiji; Saeed-Ur-Rehman
[Chemistry Letters, 1984, p. 1603 - 1606]
[4]Kotani, Shunsuke; Furusho, Haruka; Sugiura, Masaharu; Nakajima, Makoto
[Tetrahedron, 2013, vol. 69, # 14, p. 3075 - 3081]
[5]Kotani, Shunsuke; Hanamure, Takuya; Nozaki, Hirono; Sugiura, Masaharu; Nakajima, Makoto
[Tetrahedron Asymmetry, 2017, vol. 28, # 2, p. 282 - 287]

* For details of the synthesis route, please refer to the original source to ensure accuracy.