2-Pyridin-4-Yl-3H-Benzoimidazole-5-Carboxylic Acid

• CAS: 316833-32-6
• Catalog Number: ACM316833326
• Category: Other Products
• Molecular Weight: 239.23
• Molecular Formula: C13H9N3O2
• Synonyms: 2-PYRIDIN-4-YL-3H-BENZOIMIDAZOLE-5-CARBOXYLIC ACID;2-Pyridin-4-yl-3H-benzimidazole-5-carboxylic acid;2-Pyridin-4-yl-1H-benzimidazole-5-carboxylic acid
• IUPAC Name: 2-pyridin-4-yl-3H-benzimidazole-5-carboxylic acid
• InChI: InChI=1S/C13H9N3O2/c17-13(18)9-1-2-10-11(7-9)16-12(15-10)8-3-5-14-6-4-8/h1-7H,(H,15,16)(H,17,18)
• InChI Key: TYFICRRCLJYFJU-UHFFFAOYSA-N
• Density: 1.439g/cm³
• Complexity: 317
• CompoundIs Canonicalized: Yes
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Exact Mass: 239.069476538g/mol
• Formal Charge: 0
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Isotope Atom Count: 0
• Length: 0.5-2 um
• Monoisotopic Mass: 239.069476538g/mol
• Rotatable Bond Count: 2
• Topological Polar Surface Area: 78.9Ų
• Undefined Atom Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• XLogP3: 1.6

Custom Reviews

June 16, 2023

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Work great in drug synthesis
GL-0329, an anti-inflammatory drug synthesized by 2-pyridin-4-Yl-3H-benzoimidazole-5-carboxylic acid, can inhibit the secretion of IL-1β and improve the symptoms of arthritis.

Synthetic Use

Upstream Synthesis Route 1

• 872-85-5
• 619-05-6

• 316833-32-6

Reference: [1] Bulletin of the Korean Chemical Society, 2013, vol. 34, # 8, p. 2297 - 2304