2-Maleimidoacetic acid

• CAS: 25021-08-3
• Catalog Number: ACM25021083
• Category: Other Products
• Molecular Weight: 155.11
• Molecular Formula: C₆H₅NO₄
• Synonyms: 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-acetic Acid; N-(Carboxymethyl)maleimide; N-Maleimidoglycine; N-Maleoylglycine; NSC 266055
• IUPAC Name: 2-(2,5-dioxopyrrol-1-yl)acetic acid
• Canonical SMILES: C1=CC(=O)N(C1=O)CC(=O)O
• InChI Key: GBKPNGVKZQBPCZ-UHFFFAOYSA-N
• Boiling Point: 376.7ºC at 760mmHg
• Flash Point: 181.6ºC
• Density: 1.578g/cm³
• EC Number: 607-487-4
• Exact Mass: 155.02200
• H-Bond Acceptor: 4
• H-Bond Donor: 1

Synthetic Use

Upstream Synthesis Route 1

• 329709-87-7

• 25021-08-3

Reference: [1] Patent: CN105037237, 2017, B, . Location in patent: Paragraph 0059-0062

Downstream Synthesis Route 1

• 6066-82-6
• 25021-08-3

• 55750-61-3

Reference: [1] Bioconjugate Chemistry, 2012, vol. 23, # 12, p. 2417 - 2433
[2] Journal of Medicinal Chemistry, 1984, vol. 27, # 10, p. 1325 - 1335

Downstream Synthesis Route 2

• 25021-08-3

• 55750-61-3

Reference: [1] Patent: CN105037237, 2017, B,

Downstream Synthesis Route 3

• 6066-82-6
• 25021-08-3

• 55750-61-3

Reference: [1]Bioconjugate Chemistry,2012,vol. 23,p. 2417 - 2433
[2]Journal of Medicinal Chemistry,1984,vol. 27,p. 1325 - 1335

Downstream Synthesis Route 4

• 25021-08-3
• 95-95-4

• 83100-48-5

Reference: [1]Zeitschrift fur Chemie,1982,vol. 22,p. 179 - 179

* For details of the synthesis route, please refer to the original source to ensure accuracy.