2-Deoxy-2-fluoro-L-fucose

• CAS: 70763-62-1
• Catalog Number: ACM70763621
• Category: Other Products
• Molecular Weight: 166.15
• Molecular Formula: C6H11FO4
• Synonyms: (3S,4R,5S,6S)-3-Fluoro-6-methyl-tetrahydropyran-2,4,5-triol
• IUPAC Name: (2S,3R,4R,5S)-2-fluoro-3,4,5-trihydroxyhexanal
• Canonical SMILES: C[C@@H]([C@H]([C@H]([C@@H](C=O)F)O)O)O
• InChI: InChI=1S/C6H11FO4/c1-3(9)5(10)6(11)4(7)2-8/h2-6,9-11H,1H3/t3-,4+,5+,6-/m0/s1
• InChI Key: SQTFKIKSQNCWGJ-KCDKBNATSA-N
• Boiling Point: 386.5±42.0 °C
• Density: 1.335±0.06 g/ml
• Appearance: Solid
• pKa: 12.70±0.20

Custom Q&A

What is the molecular formula of 2-Deoxy-2-fluoro-L-fucose?

The molecular formula of 2-Deoxy-2-fluoro-L-fucose is C6H11FO4.

What is the molecular weight of 2-Deoxy-2-fluoro-L-fucose?

The molecular weight of 2-Deoxy-2-fluoro-L-fucose is 166.15 g/mol.

What are some synonyms for 2-Deoxy-2-fluoro-L-fucose?

Some synonyms for 2-Deoxy-2-fluoro-L-fucose include 2-fluorofucose and L-Galactose, 2,6-dideoxy-2-fluoro.

What is 2-Deoxy-2-fluoro-L-fucose under investigation for in clinical trial NCT02952989?

2-Deoxy-2-fluoro-L-fucose is under investigation as a protein fucosylation inhibitor with potential antineoplastic and immunomodulating activities.

How is 2-Deoxy-2-fluoro-L-fucose converted in the body to exert its effects?

2-Deoxy-2-fluoro-L-fucose is converted to guanosine diphosphate (GDP)-2FF, which prevents the formation of the fucosylation substrate GDP-fucose.

What role does fucosylation play in biological processes according to the reference?

Fucosylation of glycoproteins plays a key role in many biological processes, such as protein function, receptor binding, cell signaling, and cellular adhesion.

How does blocking fucosylation affect tumor cell growth?

Blocking fucosylation decreases tumor cell growth by preventing the incorporation of fucose into glycoproteins.

What is the InChIkey for 2-Deoxy-2-fluoro-L-fucose?

The InChIkey for 2-Deoxy-2-fluoro-L-fucose is SQTFKIKSQNCWGJ-KCDKBNATSA-N.

What is the UNII number for 2-Deoxy-2-fluoro-L-fucose?

The UNII number for 2-Deoxy-2-fluoro-L-fucose is W39886N0ZG.

How many hydrogen bond donor counts does 2-Deoxy-2-fluoro-L-fucose have?

2-Deoxy-2-fluoro-L-fucose has 3 hydrogen bond donor counts.