2-Amino-5-fluorobenzoxazole

• CAS: 1682-39-9
• Catalog Number: ACM1682399
• Category: Other Products
• Molecular Weight: 152.125803 [g/mol]
• Molecular Formula: C₇H₅N₂OF
• Synonyms: 5-Fluor-2-amino-benzoxazol; 5-fluoro-benzooxazol-2-ylamine; 5-Fluorobenzo[d]oxazol-2-amine; BENZOXAZOLE,2-AMINO-5-FLUORO; 5-fluorobenzoxazol-2-amine; 2-Amino-5-fluorobenzoxazole
• IUPAC Name: 5-fluoro-1,3-benzoxazol-2-amine
• Canonical SMILES: C1=CC2=C(C=C1F)N=C(O2)N
• InChI Key: PFPSBRGOJCFWKD-UHFFFAOYSA-N
• Boiling Point: 282.8ºC at 760mmHg
• Flash Point: 124.9ºC
• Density: 1.434g/cm³
• Exact Mass: 152.03900
• H-Bond Acceptor: 4
• H-Bond Donor: 1

Synthetic Use

Upstream Synthesis Route 1

• 506-68-3
• 399-97-3

• 1682-39-9

Reference: [1]Li, Dongsheng; Liu, Chao; Jiang, Xinhai; Lin, Yuan; Zhang, Jing; Li, Yan; You, Xuefu; Jiang, Wei; Chen, Minghua; Xu, Yanni; Si, Shuyi
[European Journal of Medicinal Chemistry, 2021, vol. 209]
[2]Sam,J.; Plampin,J.N.
[Journal of Pharmaceutical Sciences, 1964, vol. 53, p. 538 - 544]

Upstream Synthesis Route 2

• 371-41-5

• 1682-39-9

Reference: [1]Morofuji, Tatsuya; Shimizu, Akihiro; Yoshida, Jun-Ichi
[Chemistry - A European Journal, 2015, vol. 21, # 8, p. 3211 - 3214]