1H-Pyrrolo[2,3-b]pyridine, 1-[(4-methylphenyl)sulfonyl]-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

• CAS: 866545-91-7
• Catalog Number: ACM866545917
• Category: Other Products
• Synonyms: 1H-Pyrrolo[2,3-b]pyridine, 1-[(4-methylphenyl)sulfonyl]-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

Synthetic Use

Upstream Synthesis Route 1

• 73183-34-3
• 226085-18-3

• 866545-91-7

Reference: [1] Patent: WO2005/95400, 2005, A1, . Location in patent: Page/Page column 326; 327

Upstream Synthesis Route 2

• 76-09-5
• 882562-39-2

• 866545-91-7

Reference: [1] Patent: WO2013/70606, 2013, A1, . Location in patent: Paragraph 00393-00395

Upstream Synthesis Route 3

• 7732-18-5
• 73183-34-3
• 226085-18-3

• 866545-91-7
• 882562-39-2

Reference: [1] Patent: US2018/179199, 2018, A1, . Location in patent: Paragraph 0449-0450

Upstream Synthesis Route 4

• 73183-34-3
• 226085-18-3

• 866545-91-7

Reference: [1]Current Patent Assignee: VERTEX PHARMACEUTICALS (OLD) - WO2005/95400, 2005, A1
Location in patent: Page/Page column 326; 327
[2]Current Patent Assignee: Cheil Industries Co., Ltd.; Hong, Jin Suk; Yu, Dong Gyu; Yu, Uhn Sun; Lee, Han Ir; Kang, Dong Min; Lee, Sang Sin; Jang, Yuna; Jung, Su Young; Han, Su Jin - KR2015/15252, 2015, A
Location in patent: Paragraph 0182;0183
[3]Wang, Ruifeng; Chen, Yixuan; Yang, Bowen; Yu, Sijia; Zhao, Xiangxin; Zhang, Cai; Hao, Chenzhou; Zhao, Dongmei; Cheng, Maosheng
[Bioorganic Chemistry, 2020, vol. 94]
[4]Farmer, Luc J.; Ledeboer, Mark W.; Hoock, Thomas; Arnost, Michael J.; Bethiel, Randy S.; Bennani, Youssef L.; Black, James J.; Brummel, Christopher L.; Chakilam, Ananthsrinivas; Dorsch, Warren A.; Fan, Bin; Cochran, John E.; Halas, Summer; Harrington, Edmund M.; Hogan, James K.; Howe, David; Huang, Hui; Jacobs, Dylan H.; Laitinen, Leena M.; Liao, Shengkai; Mahajan, Sudipta; Marone, Valerie; Martinez-Botella, Gabriel; McCarthy, Pamela; Messersmith, David; Namchuk, Mark; Oh, Luke; Penney, Marina S.; Pierce, Albert C.; Raybuck, Scott A.; Rugg, Arthur; Salituro, Francesco G.; Saxena, Kumkum; Shannon, Dean; Shlyakter, Dina; Swenson, Lora; Tian, Shi-Kai; Town, Christopher; Wang, Jian; Wang, Tiansheng; Wannamaker, M. Woods; Winquist, Raymond J.; Zuccola, Harmon J.
[Journal of Medicinal Chemistry, 2015, vol. 58, # 18, p. 7195 - 7216]

Downstream Synthesis Route 1

• 49844-90-8
• 866545-91-7

• 866545-92-8

Reference: [1]Patent: WO2005/95400,2005,A1 .Location in patent: Page/Page column 326; 327-328

Downstream Synthesis Route 2

• 866545-91-7
• 71406-74-1

• 1052631-05-6

Reference: [1]Patent: WO2005/95400,2005,A1 .Location in patent: Page/Page column 326; 329-330

* For details of the synthesis route, please refer to the original source to ensure accuracy.