1-dodecyl-3-methylimidazolium chloride

• CAS: 114569-84-5
• Catalog Number: ACM114569845
• Category: Main Products
• Molecular Weight: 286.88
• Molecular Formula: C16H31N2Cl
• Synonyms: 1-dodecyl-3-methylimidazol-3-ium,chloride1-dodecyl-3-methylimidazolium chloride
• Melting Point: 150 °C
• Appearance: White to yellow powder and block
• Application: Ionic liquid
• Storage: Closed in a cool and dry environment
• Chemical Formula: [C12MIm]Cl

Case Study

Performance of 1-Dodecyl-3-Methylimidazolium Chloride as A Surfactant

Hezave, Ali Zeinolabedini, et al. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2013, 421, 63-71.

1-dodecyl-3-methylimidazolium chloride ([C12mim] [Cl]) is an ionic liquid (IL) that can be used as a surfactant to reduce the interfacial tension (IFT) of crude oil. The research investigated the dynamic interfacial tension of aqueous solutions of 1-dodecyl-3-methylimidazolium chloride at varying concentrations, with and without NaCl ions, and at temperatures ranging from 293.15 to 333.15K.
[C12mim] [Cl] Effect on water/oil IFT
· The concentration of the IL increased from 0 to 100, there was a significant decrease in interfacial tension (from 39.98 to 0.81 mN/m), leveling off after reaching the critical micelle concentration (CMC).
· Additionally, the IL maintained its ability to reduce interfacial tension even in high salinity conditions, making it a promising agent for tertiary enhanced oil recovery.
· Furthermore, three adsorption tests indicated that the presence of brine and oil could increase the loss of IL during the flooding process, particularly in instances where both brine and oil were present in the rock's pore structure. Core flooding experiments confirmed the efficacy of IL solutions as a means to recover more residual oil trapped in the rock formation following waterflooding operations.

Cytotoxicity Evaluation of 1-Dodecyl-3-Methylimidazolium Chloride

Wang, Peijin, et al. Environmental toxicology, 2020, 35(6), 665-672.

This work studied the cytotoxicity of 1-dodecyl-3-methylimidazole chloride ([C12min]Cl) ionic liquid on human hepatocellular carcinoma (HepG2) cells. The evaluation included cell viability, genotoxicity, Oxidative stress, apoptosis, cell cycle and apoptosis-related gene expression. The results show that [C12min]Cl has genotoxicity, physiological toxicity and promotes cell apoptosis on HepG2 cells.
[C12min]Cl exposure and cell viability assay
· After incubating the cells in a 96-well culture plate with a density of 1.0 × 104 cells per well for 24 hours to allow for cell adherence and growth, cells were cultured with different concentrations of [C12min]Cl (0.2, 0.6, 1.0, and 1.4 μg/mL), along with a control group with no [C12min]Cl.
· Cell viability after 12, 24, and 48 hours of exposure was assessed using the MTT assay, where metabolically active cells convert tetrazolium salt into formazan crystals. Following exposure, MTT solution (5 mg/mL) was added to each well, incubated for 4 hours in a CO2 incubator at 37°C, then dimethyl sulfoxide was added and the color developed was read at 490 nm.
· The untreated groups served as controls and underwent the same procedures. Cell viability was calculated as the percentage absorption of exposed cells compared to controls. Based on the inhibitory rates of HepG2 cells after 24 hours of [C12min]Cl exposure, the half-maximal inhibitory concentration (IC50) for 24 hours was determined.

Custom Q&A

What is the molecular formula of 1-dodecyl-3-methylimidazolium chloride?

The molecular formula of 1-dodecyl-3-methylimidazolium chloride is C16H31ClN2.

When was 1-dodecyl-3-methylimidazolium chloride created?

1-dodecyl-3-methylimidazolium chloride was created on July 19, 2005.

What is the molecular weight of 1-dodecyl-3-methylimidazolium chloride?

The molecular weight of 1-dodecyl-3-methylimidazolium chloride is 286.9 g/mol.

How many hydrogen bond donor counts does 1-dodecyl-3-methylimidazolium chloride have?

1-dodecyl-3-methylimidazolium chloride does not have any hydrogen bond donor count.

What is the topological polar surface area of 1-dodecyl-3-methylimidazolium chloride?

The topological polar surface area of 1-dodecyl-3-methylimidazolium chloride is 8.8 Å2.

What is the formal charge of 1-dodecyl-3-methylimidazolium chloride?

The formal charge of 1-dodecyl-3-methylimidazolium chloride is 0.

How many rotatable bond counts does 1-dodecyl-3-methylimidazolium chloride have?

1-dodecyl-3-methylimidazolium chloride has 11 rotatable bond counts.

Is 1-dodecyl-3-methylimidazolium chloride a covalently-bonded unit?

Yes, 1-dodecyl-3-methylimidazolium chloride is a covalently-bonded unit.

What is the InChIKey of 1-dodecyl-3-methylimidazolium chloride?

The InChIKey of 1-dodecyl-3-methylimidazolium chloride is OPXNHKQUEXEWAM-UHFFFAOYSA-M.

When was the last modification made to the information about 1-dodecyl-3-methylimidazolium chloride?

The last modification was made on December 30, 2023.