1,2-Dihydro-2-oxo-spiro[3h-indole-3,4'-piperidine]-1'-carboxylic acid 1,1-dimethylethyl ester

• CAS: 252882-60-3
• Catalog Number: ACM252882603
• Category: Other Products
• Molecular Weight: 302.368180 [g/mol]
• Molecular Formula: C₁₇H₂₂N₂O₃
• Synonyms: 252882-60-3, 1-Boc-1,2-dihydro-2-oxo-spiro[3H-indole-3,4-piperidine], tert-butyl 2-oxospiro[indoline-3,4-piperidine]-1-carboxylate, tert-butyl 2-oxo-1H-spiro[indole-3,4-piperidine]-1-carboxylate, TERT-BUTYL 2-OXOSPIRO[INDOLINE-3.4-PIPERIDINE]-1-CARBOXYLATE, SureCN1195957, CTK4F5384, MolPort-009-197-392, ACN-S001320, JALOR-CHEM I14-12316, ANW-52242, AKOS015836953, AG-E-77035, PB13153, AK-24410, AM803585, BR-24410, KB-60931, AB1010299, W4859
• IUPAC Name: tert-butyl 2-oxospiro[1H-indole-3,4-piperidine]-1-carboxylate
• InChI Key: YEJCWMVHDBKPBN-UHFFFAOYSA-N
• Boiling Point: 475.6ºC at 760 mmHg
• Flash Point: 241.4ºC
• Density: 1.22g/cm³
• Exact Mass: 302.16300
• H-Bond Acceptor: 3
• H-Bond Donor: 1

Synthetic Use

Upstream Synthesis Route 1

• 252882-61-4
• 24424-99-5

• 252882-60-3

Reference: [1] Patent: WO2014/60411, 2014, A1, . Location in patent: Page/Page column 36; 37

Upstream Synthesis Route 2

• 59-48-3
• 118753-70-1

• 252882-60-3

Reference: [1] Journal of Medicinal Chemistry, 2012, vol. 55, # 7, p. 2945 - 2959
[2] Patent: US6172076, 2001, B2,
[3] Patent: WO2008/144266, 2008, A1, . Location in patent: Page/Page column 25-26

Upstream Synthesis Route 3

• 59-48-3
• 118753-70-1

• 252882-60-3

Reference: [1]Journal of Medicinal Chemistry,2012,vol. 55,p. 2945 - 2959
[2]Patent: US6172076,2001,B2
[3]Patent: WO2008/144266,2008,A1 .Location in patent: Page/Page column 25-26

Downstream Synthesis Route 1

• 252882-60-3

• 252882-61-4

Reference: [1] Patent: WO2007/28638, 2007, A1, . Location in patent: Page/Page column 96

Downstream Synthesis Route 2

• 252882-60-3

• 252882-61-4

Reference: [1]Patent: WO2007/28638,2007,A1 .Location in patent: Page/Page column 96

* For details of the synthesis route, please refer to the original source to ensure accuracy.