Kanamycin sulfate

• CAS: 70560-51-9
• Catalog Number: ACM70560519
• Category: Main Products
• Molecular Weight: 582.58
• Molecular Formula: C₁₈H₃₈N₄O₁₅S
• Synonyms: KANAMYCIN MONOSULFATE;KANAMYCIN MONOSULFATE SALT;KANAMYCIN MONO SULPHATE;KAMYCIN;KANAMYCIN ACID SULFATE;KANAMYCIN A SULFATE SALT;KANAMYCIN SULFATE SALT;KANAMYCIN SULFATE, STREPTOMYCES KANAMYCETICUS
• IUPAC Name: KANAMYCIN SULFATE
• Boiling Point: 943.2ºC at 760 mmHg
• Melting Point: 250ºC
• Flash Point: 524.2ºC
• Appearance: powder
• Exact Mass: 582.20500
• Hazard Statements: Xi,T
• Safety Description: 22-24/25-53-45-36/37/39
• Supplemental Hazard Statements: H360
• Symbol: GHS08
• WGK Germany: 3

Case Study

Kanamycin Sulfate Used for the Development of Cellulose-Based Antibacterial Materials

Gu G, et al. International Journal of Biological Macromolecules, 2022, 194, 435-444.

Kanamycin sulfate (KS) was utilized to synthesize eco-friendly and stable cellulose-based antibacterial materials with broad-spectrum antimicrobial activity. The material was prepared by cross-linking KS with α-cellulose using glutaraldehyde (GA) as a cross-linking agent.
The synthesis involved dispersing α-cellulose in an acidic aqueous solution containing varying KS-to-cellulose mass ratios (1:200, 1:100, and 1:10). After initial mixing, GA was added to facilitate cross-linking, and the reaction was conducted under controlled stirring in the dark for 12 hours. The resulting products, named KSC 1/200, KSC 1/100, and KSC 1/10, were thoroughly washed and freeze-dried. A control sample (CL), consisting of pure α-cellulose treated under identical conditions without KS, was also prepared for comparison.
The integration of KS into the cellulose matrix enhanced the material's antibacterial efficacy, offering a potential solution for the development of sustainable and cost-effective antimicrobial systems.