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Structure

Ivabradine hydrochloride

CAS
148849-67-6
Catalog Number
ACM148849676
Category
Other Products
Molecular Weight
505.05
Molecular Formula
C27H36N2O5.HCl

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Specification

Synonyms
Ivabradine HCl;Ivabradine hydrochloride;3-[3-[[(8S)-3,4-Dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochloride;3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one Hydrochloride;Corlentor;Procoralan;S-16257;(7,8-Dimethoxy 3-(3-(((1S)-(4,5-dimethoxybenzocyclobutan-1-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-2H-benzazepin-2-one hydrochloride
Melting Point
193-196?C
Hazard Statements
N
Safety Description
60-61
Supplemental Hazard Statements
H400
Symbol
GHS09
What is the molecular formula of Ivabradine hydrochloride?

The molecular formula of Ivabradine hydrochloride is C27H37ClN2O5.

What is the molecular weight of Ivabradine hydrochloride?

The molecular weight of Ivabradine hydrochloride is 505.0 g/mol.

What is the role of Ivabradine hydrochloride as?

Ivabradine hydrochloride is described as a cardiotonic drug used to treat patients with angina intolerant to beta blockers and/or heart failure.

How does Ivabradine hydrochloride work in the body to lower heart rate?

Ivabradine hydrochloride selectively binds to the intracellular portion of the HCN channel pore and blocks HCN channels in the pacemaker cells within the sinoatrial (SA) node, inhibiting the If pacemaker ion current.

What is the IUPAC Name of Ivabradine hydrochloride?

The IUPAC Name of Ivabradine hydrochloride is 3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one;hydrochloride.

What is the InChIKey of Ivabradine hydrochloride?

The InChIKey of Ivabradine hydrochloride is HLUKNZUABFFNQS-ZMBIFBSDSA-N.

What is the CAS number of Ivabradine hydrochloride?

The CAS number of Ivabradine hydrochloride is 148849-67-6.

How does Ivabradine hydrochloride affect the regulation of pacemaker firing rate in the SA node?

Ivabradine hydrochloride blocks HCN channels involved in the regulation of pacemaker firing rate in the SA node, reducing heart rate.

What are some synonyms for Ivabradine hydrochloride?

Some synonyms for Ivabradine hydrochloride include Ivabradine HCl, Procoralan, and Corlentor.

When was Ivabradine hydrochloride first created and when was it last modified?

Ivabradine hydrochloride was created on August 9, 2005, and last modified on December 30, 2023.

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