148-53-8 Purity
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Specification
The molecular formula of Ivabradine hydrochloride is C27H37ClN2O5.
The molecular weight of Ivabradine hydrochloride is 505.0 g/mol.
Ivabradine hydrochloride is described as a cardiotonic drug used to treat patients with angina intolerant to beta blockers and/or heart failure.
Ivabradine hydrochloride selectively binds to the intracellular portion of the HCN channel pore and blocks HCN channels in the pacemaker cells within the sinoatrial (SA) node, inhibiting the If pacemaker ion current.
The IUPAC Name of Ivabradine hydrochloride is 3-[3-[[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one;hydrochloride.
The InChIKey of Ivabradine hydrochloride is HLUKNZUABFFNQS-ZMBIFBSDSA-N.
The CAS number of Ivabradine hydrochloride is 148849-67-6.
Ivabradine hydrochloride blocks HCN channels involved in the regulation of pacemaker firing rate in the SA node, reducing heart rate.
Some synonyms for Ivabradine hydrochloride include Ivabradine HCl, Procoralan, and Corlentor.
Ivabradine hydrochloride was created on August 9, 2005, and last modified on December 30, 2023.