Fluorescein, disodium salt

• CAS: 518-47-8
• Catalog Number: ACM518478
• Category: Main Products
• Molecular Weight: 376.28
• Molecular Formula: C20H10Na2O5
• Storage: -20°C in the dark
• Excitation Maximum: 490

Case Study

Uranine-Based Composites for Preparation of Inorganic Phosphate Fluorescent Probes

Li, Huihui, et al. Sensors and Actuators B: Chemical, 2019, 301, 127110.

Fluorescein disodium salt, also known as uranine, has a high quantum yield, which is beneficial to improving the detection sensitivity of inorganic phosphate (Pi). In addition, anionic uranium facilitates the loading of zeolite imidazolate framework-8 (ZIF-8), which is widely used in fluorescence sensing.
Synthesis of uranine@ZIF-8 composite
· 0.2 g Zn(NO3)2·6H2O was dissolved in 0.8 mL water (pH 8, adjusted by NaOH), and then the solution of 12 mg uranine in 4 mL water was added.
· After the mixture was stirred at room temperature for 1 min, the solution of 2 g 2-methylimidazole in 8 mL water was added dropwise.
· The mixture was stirred at room temperature for an additional 15 min, and then the obtained uranine@ZIF-8 were collected by centrifugation.
· After washed with water/ethanol (1/1, v/v) for several times, uranine@ZIF-8 was dried under vacuum at 60 °C overnight.