Doxorubicin hydrochloride

• CAS: 25316-40-9
• Catalog Number: ACM25316409
• Category: Main Products
• Molecular Weight: 579.98
• Molecular Formula: C₂₇H₃₀ClNO₁₁
• Synonyms: ADRIACIN;ADRIBLASTINA;ADRIBLASTINA HYDROCHLORIDE;ADRIAMYCIN HCL;ADRIAMYCIN HYDROCHLORIDE;(8s-cis)-10-[(3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dione hydrochloride;14-HYDROXYDAUNOMYCIN HCL;14-HYDROXYDAUNOMYCIN HYDROCHLORIDE
• IUPAC Name: (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride
• Canonical SMILES: CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
• InChI Key: MWWSFMDVAYGXBV-RUELKSSGSA-N
• Boiling Point: 810.3ºC at 760 mmHg
• Melting Point: 216°C (dec.)(lit.)
• Flash Point: 443.8ºC
• Appearance: Orange-Red Crystalline Solid
• EC Number: 246-818-3
• Exact Mass: 579.15100
• Hazard Statements: T,T+,Xi
• Safety Description: 53-45-36/37/39-22-7/9
• Stability: Stable at room temperature in closed containers under normal storage and handling conditions.
• Supplemental Hazard Statements: H351-H361-H373-H302-H315-H319-H350
• Symbol: GHS07,GHS08
• WGK Germany: 3

Synthetic Use

Upstream Synthesis Route 1

• 29742-67-4

• 25316-40-9

Reference: [1] Carbohydrate Research, 1988, vol. 184, p. 231 - 235

Upstream Synthesis Route 2

• 23541-50-6

• 25316-40-9

Reference: [1] Carbohydrate Research, 1988, vol. 184, p. 231 - 235

Downstream Synthesis Route 1

• 108-30-5
• 25316-40-9

• 123106-18-3

Reference: [1]Synthetic Communications,2002,vol. 32,p. 1961 - 1975

* For details of the synthesis route, please refer to the original source to ensure accuracy.