950569-46-7 Purity
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Specification
The molecular formula of gemcitabine is C9H11F2N3O4.
The synonyms of gemcitabine are gemcitabine, 95058-81-4, 2'-Deoxy-2',2'-difluorocytidine, and 2',2'-Difluorodeoxycytidine.
The molecular weight of gemcitabine is 263.20 g/mol.
Gemcitabine has multiple roles including as a photosensitizing agent, a DNA synthesis inhibitor, a prodrug, an EC 1.17.4.1 (ribonucleoside- diphosphate reductase) inhibitor, an environmental contaminant, a xenobiotic, a radiosensitizing agent, an antineoplastic agent, an antimetabolite, an antiviral drug, and an immunosuppressive agent.
Gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer, and breast cancer.
The ChEBI ID of gemcitabine is CHEBI888.
The mechanism of action of gemcitabine is as a Nucleic Acid Synthesis Inhibitor.
Gemcitabine is approved by the FDA to treat advanced ovarian cancer in combination with carboplatin, metastatic breast cancer in combination with paclitaxel, non-small cell lung cancer in combination with cisplatin, and pancreatic cancer as monotherapy.
The CAS number of gemcitabine is 95058-81-4.
Other identifiers of gemcitabine include UNII B76N6SBZ8R, ChEMBL ID CHEMBL888, and DSSTox Substance ID DTXSID3040487.