Gemcitabine

CAS
950-58-81-4
Catalog Number
ACM95058814
Category
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Specification

Synonyms
Gemcitabine
What is the molecular formula of gemcitabine?

The molecular formula of gemcitabine is C9H11F2N3O4.

What are the synonyms of gemcitabine?

The synonyms of gemcitabine are gemcitabine, 95058-81-4, 2'-Deoxy-2',2'-difluorocytidine, and 2',2'-Difluorodeoxycytidine.

What is the molecular weight of gemcitabine?

The molecular weight of gemcitabine is 263.20 g/mol.

What is the role of gemcitabine?

Gemcitabine has multiple roles including as a photosensitizing agent, a DNA synthesis inhibitor, a prodrug, an EC 1.17.4.1 (ribonucleoside- diphosphate reductase) inhibitor, an environmental contaminant, a xenobiotic, a radiosensitizing agent, an antineoplastic agent, an antimetabolite, an antiviral drug, and an immunosuppressive agent.

What is gemcitabine used to treat?

Gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer, and breast cancer.

What is the ChEBI ID of gemcitabine?

The ChEBI ID of gemcitabine is CHEBI888.

What is the mechanism of action of gemcitabine?

The mechanism of action of gemcitabine is as a Nucleic Acid Synthesis Inhibitor.

What are the approved uses of gemcitabine?

Gemcitabine is approved by the FDA to treat advanced ovarian cancer in combination with carboplatin, metastatic breast cancer in combination with paclitaxel, non-small cell lung cancer in combination with cisplatin, and pancreatic cancer as monotherapy.

What is the CAS number of gemcitabine?

The CAS number of gemcitabine is 95058-81-4.

What are the other identifiers of gemcitabine?

Other identifiers of gemcitabine include UNII B76N6SBZ8R, ChEMBL ID CHEMBL888, and DSSTox Substance ID DTXSID3040487.

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