91031-63-9 Purity
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Specification
The molecular formula of teicoplanin is C88H97Cl2N9O33.
The molecular weight of teicoplanin is 1879.7 g/mol.
Teicoplanin is a glycopeptide antibiotic complex consisting of a mixture of several compounds, including five major and four minor components.
Teicoplanin inhibits peptidoglycan polymerization, resulting in the inhibition of bacterial cell wall synthesis and cell death.
Teicoplanin is isolated from the bacterium Actinoplanes teichomyceticus.
The IUPAC name of teicoplanin is (1S,2R,19R,22R,34S,37R,40R,52S)-2-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-22-amino-5,15-dichloro-64-[(2S,3R,4R,5S,6R)-3-(decanoylamino)-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-26,31,44,49-tetrahydroxy-21,35,38,54,56,59-hexaoxo-47-[(3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-7,13,28-trioxa-20,36,39,53,55,58-hexazaundecacyclo[38.14.2.2 3,6 .2 14,17 .2 19,34 .1 8,12 .1 23,27 .1 29,33 .1 41,45 .0 10,37 .0 46,51 ]hexahexaconta-3,5,8,10,12(64),14,16,23(61),24,26,29(60),30,32,41(57),42,44,46(51),47,49,62,65-henicosaene-52-carboxylic acid.
The InChIKey of teicoplanin is BJNLLBUOHPVGFT-CAYRISATSA-N.
Some synonyms for teicoplanin include Targocid, Antibiotic 8327A, and Teichomycin.
The CAS number of teicoplanin is 61036-62-2.
All teicoplanins share a same glycopeptide core, teicoplanin A3-1, but differ in the length and conformation of side chains attached to their β-D-glucosamine moiety.