2,2-Difluorobenzodioxole-5-carboxaldehyde

CAS

656-42-8

Catalog Number

ACM656428

Category

Other Products

Molecular Weight

186.11

Molecular Formula

C₈H₄F₂O₃

MSDS COA Spec Sheet

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Upstream Synthesis Route 1

33070-32-5
68-12-2

656-42-8

Reference: [1] Patent: US2007/37815, 2007, A1, . Location in patent: Page/Page column 20

Upstream Synthesis Route 2

1269252-03-0

656-42-8

Reference: [1] Organic and Biomolecular Chemistry, 2011, vol. 9, # 3, p. 902 - 905

Upstream Synthesis Route 3

149045-78-3
100-97-0

656-42-8

Reference: [1] Patent: US5420308, 1995, A,

Downstream Synthesis Route 1

656-42-8
141-82-2

387350-55-2

Reference: [1]Current Patent Assignee: ROCHE HOLDING AG - WO2004/96796, 2004, A1
Location in patent: Page 33

Downstream Synthesis Route 2

656-42-8

1346528-50-4

Reference: [1]Patent: WO2011/139951,2011,A1

Downstream Synthesis Route 3

110-85-0
656-42-8

1093211-85-8

Reference: [1]Current Patent Assignee: JOHNSON & JOHNSON INC - WO2011/139951, 2011, A1
Location in patent: Page/Page column 23-24
[2]Location in patent: experimental part
Liu, Jing; Fitzgerald, Anne E.; Mani, Neelakandha S.
[Synthesis, 2012, vol. 44, # 15, p. 2469 - 2473]
[3]Keith, John M.; Jones, William M.; Tichenor, Mark; Liu, Jing; Seierstad, Mark; Palmer, James A.; Webb, Michael; Karbarz, Mark; Scott, Brian P.; Wilson, Sandy J.; Luo, Lin; Wennerholm, Michelle L.; Chang, Leon; Rizzolio, Michele; Rynberg, Raymond; Chaplan, Sandra R.; Breitenbucher, J. Guy
[ACS Medicinal Chemistry Letters, 2015, vol. 6, # 12, p. 1204 - 1208]

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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