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Structure

2-Amino-isonicotinic acid hydrazide

CAS
58481-01-9
Catalog Number
ACM58481019
Category
Other Products
Molecular Weight
152.15
Molecular Formula
C6H8N4O

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  • Case Study
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  • Synthetic Use
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Specification

Synonyms
Isoniazid analog, Ambad88, 2-Aminoisonicotinic acid hydrazide, AIDS070057, 2-Amino-isonicotinic acid hydrazide, AIDS-070057, NSC280612, 58481-01-9
IUPAC Name
2-aminopyridine-4-carbohydrazide
Canonical SMILES
C1=CN=C(C=C1C(=O)NN)N
InChI Key
JWUWTBDKCYJSLE-UHFFFAOYSA-N
Melting Point
190.9-191.3ºC
Density
1.352 g/cm³
Exact Mass
152.07000
Hazard Statements
Xi
H-Bond Acceptor
4
H-Bond Donor
3
Safety Description
S24/25

Upstream Synthesis Route 1

  • 6937-03-7
  • 58481-01-9

Reference: [1]Abd El-Salam, Osama I.; Mohamed, Salwa F.
[Journal of the Chinese Chemical Society, 2005, vol. 52, # 6, p. 1157 - 1164]
[2]Location in patent: scheme or table
Zhang, Li-Rong; Liu, Zhi-Jun; Zhang, Hui; Sun, Jian; Luo, Yin; Zhao, Ting-Ting; Gong, Hai-Bin; Zhu, Hai-Liang
[Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 11, p. 3615 - 3621]
[3]Current Patent Assignee: CHINESE ACADEMY OF SCIENCES; Shanghai Institute of Materia Medica (in: CAS) - CN110818683, 2020, A
Location in patent: Paragraph 0197; 0236-0237

Downstream Synthesis Route 1

  • 58481-01-9
  • 14527-26-5
  • 77314-44-4

Reference: [1]Journal of Medicinal Chemistry,1985,vol. 28,p. 1628 - 1636

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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