4-Hydroxyquinazoline

CAS

491-36-1

Catalog Number

ACM491361

Category

Other Products

Molecular Weight

146.15

Molecular Formula

C8H6N2O

MSDS COA Spec Sheet

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Specification

Synonyms

4-Quinazolinol; 4-oxo-3,4-dihydroquinazoline; 3,4-dihydroquinazolin-4-one; quinazoline-4(3H)-one; Quinazolin-4-one; quinazolin-4(3H)-one; QUINAZOLIN-4-OL; 4-HQN; 4-QUINAZOLINO; QUINAZOLONE; 3H-quinazolinyl-4-one; QUINAZOLINONE; Quinazolone,4; 4-QUINAZOLON

IUPAC Name

1H-quinazolin-4-one

Canonical SMILES

C1=CC=C2C(=C1)C(=O)N=CN2

InChI Key

QMNUDYFKZYBWQX-UHFFFAOYSA-N

Boiling Point

303.5ºC at 760 mmHg

Melting Point

215-219ºC

Flash Point

137.3ºC

Density

1.31 g/cm³

Appearance

White Solid

EC Number

207-735-8

Exact Mass

146.04800

Hazard Statements

Xn:Harmful

H-Bond Acceptor

H-Bond Donor

Safety Description

S22-S26-S36/37/39

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

WGK Germany

Downstream Synthesis Route 1

491-36-1

19815-16-8

Reference: [1] ChemMedChem, 2013, vol. 8, # 6, p. 928 - 933

Downstream Synthesis Route 2

491-36-1

19815-16-8

Reference: [1] Journal of Labelled Compounds and Radiopharmaceuticals, 2012, vol. 55, # 14, p. 477 - 483

Downstream Synthesis Route 3

491-36-1

15018-66-3

Reference: [1] Tetrahedron Letters, 2004, vol. 45, # 22, p. 4241 - 4243
[2] Tetrahedron Letters, 2009, vol. 50, # 40, p. 5631 - 5632

Downstream Synthesis Route 4

491-36-1
2832-19-1

70395-29-8

Reference: [1]Journal of Organic Chemistry,1952,vol. 17,p. 149,153

Downstream Synthesis Route 5

491-36-1
106-96-7

16347-56-1

Reference: [1]Głowacka, Iwona E.; Grzonkowski, Piotr; Lisiecki, Paweł; Kalinowski, Łukasz; Piotrowska, Dorota G.
[Archiv der Pharmazie, 2019, vol. 352, # 3]

Downstream Synthesis Route 6

491-36-1
62-53-3

16347-60-7

Reference: [1]Xiao, Zili; Yang, Michael G.; Li, Peng; Carter, Percy H.
[Organic Letters, 2009, vol. 11, # 6, p. 1421 - 1424]
[2]Leonard; Ruyle
[Journal of Organic Chemistry, 1948, vol. 13, p. 903,908]

* For details of the synthesis route, please refer to the original source to ensure accuracy.