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Structure

Thiourea,N-(2-hydroxyphenyl)-

CAS
1520-26-9
Catalog Number
ACM1520269
Category
Other Products
Molecular Weight
168.22
Molecular Formula
C7H8N2OS

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Specification

Synonyms
2-HYDROXYPHENYLTHIOUREA;1-(2-HYDROXYPHENYL)-2-THIOUREA;1-(o-Hydroxyphenyl)thiourea;N-(2-Hydroxyphenyl)thiourea, 97%
Density
1.45g/cm³

Upstream Synthesis Route 1

  • 53514-41-3
  • 1520-26-9

Reference: [1]Current Patent Assignee: NATIONAL HEALTH RESEARCH INSTITUTES; UNIVERSITY OF MINNESOTA SYSTEM - US2017/56377, 2017, A1
Location in patent: Paragraph 0247; 0248; 0249
[2]Douglass; Dains
[Journal of the American Chemical Society, 1934, vol. 56, p. 1408]
[3]Meissner, Anja; Boshoff, Helena I.; Vasan, Mahalakshmi; Duckworth, Benjamin P.; Barry III, Clifton E.; Aldrich, Courtney C.
[Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 21, p. 6385 - 6397]
[4]Rödl, Carmen B.; Vogt, Dominik; Kretschmer, Simon B.M.; Ihlefeld, Katja; Barzen, Sebastian; Brüggerhoff, Astrid; Achenbach, Janosch; Proschak, Ewgenij; Steinhilber, Dieter; Stark, Holger; Hofmann, Bettina
[European Journal of Medicinal Chemistry, 2014, vol. 84, p. 302 - 311]
[5]Vogt, Dominik; Weber, Julia; Ihlefeld, Katja; Brüggerhoff, Astrid; Proschak, Ewgenij; Stark, Holger
[Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 19, p. 5354 - 5367]

Downstream Synthesis Route 1

  • 1520-26-9
  • 52112-66-0

Reference: [1] Journal of the Chemical Society, 1934, p. 1186,1190

Downstream Synthesis Route 2

  • 1520-26-9
  • 7471-03-6

Reference: [1] Medicinal Chemistry Research, 2012, vol. 21, # 7, p. 1136 - 1148
[2] Journal of Medicinal Chemistry, 2016, vol. 59, # 21, p. 9814 - 9824

Downstream Synthesis Route 3

  • 1520-26-9
  • 42981-08-8
  • 67241-22-9

Reference: [1]Journal of Pharmaceutical Sciences,1978,vol. 67,p. 587 - 589

Downstream Synthesis Route 4

  • 1520-26-9
  • 52112-66-0

Reference: [1]Journal of the Chemical Society,1934,p. 1186,1190

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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