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Structure

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester

CAS
112811-71-9
Catalog Number
ACM112811719
Category
Other Products
Molecular Weight
323.29
Molecular Formula
C16H15F2NO4

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Specification

Synonyms
1-CYCLOPROPYL-6,7-DIFLUORO-8-METHOXY-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER;1-CYCLOPROPYL-6,7-DIFLUORO-1,4-DIHYDRO-8-METHOXY-4-OXO-3-QUINOLINE CARBOXYLIC ACID ETHYL ESTER;GATIFLOXACIN CARBOXYLIC ACID ETHYL ESTER;3-Quinoline Carboxylic A
Density
1.414g/cm³
Appearance
Pale Yellow Solid

Upstream Synthesis Route 1

  • 765-30-0
  • 112811-71-9

Reference: [1] Patent: EP2957561, 2015, A1, . Location in patent: Paragraph 0063; 0067-0069

Upstream Synthesis Route 2

  • 112811-70-8
  • 112811-71-9

Reference: [1] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 11, p. 2773 - 2776
[2] European Journal of Medicinal Chemistry, 2006, vol. 41, # 12, p. 1478 - 1493
[3] Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 5, p. 2558 - 2569
[4] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 4, p. 948 - 956
[5] Patent: US4980470, 1990, A,

Upstream Synthesis Route 3

  • 112811-65-1
  • 112811-71-9

Reference: [1] European Journal of Medicinal Chemistry, 2006, vol. 41, # 12, p. 1478 - 1493
[2] Journal of Medicinal Chemistry, 1995, vol. 38, # 22, p. 4478 - 4487
[3] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 4, p. 948 - 956
[4] Patent: EP2957561, 2015, A1,
[5] Patent: US4980470, 1990, A,

Downstream Synthesis Route 1

  • 112811-71-9
  • 847233-56-1

Reference: [1]Bioorganic and Medicinal Chemistry Letters,2007,vol. 17,p. 1924 - 1929
[2]Patent: WO2005/111030,2005,A1 .Location in patent: Page/Page column 57

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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