Abiraterone

• CAS: 154229-19-3
• Catalog Number: ACM154229193
• Category: Steroidal Compounds
• Molecular Weight: 349.51
• Molecular Formula: C₂₄H₃₁NO
• Synonyms: Abiraterone; (3beta)-17-(3-pyridinyl)-androsta-5,16-dien-3-ol
• IUPAC Name: (3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-pyridin-3-yl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol
• Canonical SMILES: CC12CCC(CC1=CCC3C2CCC4(C3CC=C4C5=CN=CC=C5)C)O
• InChI Key: GZOSMCIZMLWJML-VJLLXTKPSA-N
• Boiling Point: 500.2ºC at 760mmHg
• Flash Point: 256.3ºC
• Density: 1.14g/cm³
• Appearance: white solid
• Exact Mass: 349.24100

Custom Q&A

What is the molecular formula of Abiraterone?

The molecular formula of Abiraterone is C24H31NO.

What is the molecular weight of Abiraterone?

The molecular weight of Abiraterone is 349.5 g/mol.

What is the IUPAC name of Abiraterone?

The IUPAC name of Abiraterone is (3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-pyridin-3-yl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol.

What is the InChI of Abiraterone?

The InChI of Abiraterone is InChI=1S/C24H31NO/c1-23-11-9-18(26)14-17(23)5-6-19-21-8-7-20(16-4-3-13-25-15-16)24(21,2)12-10-22(19)23/h3-5,7,13,15,18-19,21-22,26H,6,8-12,14H2,1-2H3/t18-,19-,21-,22-,23-,24+/m0/s1.

What is the molecular structure of Abiraterone?

The molecular structure of Abiraterone is a 3beta-sterol that is androsta-5,16-dien-3beta-ol substituted at position 17 by a 3-pyridyl group.

What is the role of Abiraterone as a drug?

Abiraterone has a role as an antineoplastic agent and an EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor. It is used for the treatment of metastatic castrate-resistant prostate cancer.

When was Abiraterone created?

Abiraterone was created on August 8, 2005.

When was Abiraterone last modified?

Abiraterone was last modified on December 2, 2023.

What prodrug form is Abiraterone administered as?

Abiraterone is administered as the O-acetate prodrug.

When was Abiraterone approved by the FDA?

Abiraterone was FDA approved on April 28, 2011.