8,8-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bisnaphthalene-1,3,5-trisulphonic acid

CAS

145-63-1

Catalog Number

ACM145631

Category

Other Products

Molecular Weight

1297.2797

Molecular Formula

C₅₁H₄₀N₆O₂₃S₆

MSDS COA Spec Sheet

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Specification

Synonyms

8,8-[carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]]bisnaphthalene-1,3,5-trisulphonic acid;Farma 939;Fourneau;Naphuride;Suramine;129-46-4(Hexasodium salt);8,8-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonyl-imino]]bis-1,3,5-naphthalenetrisulfonic acid;Aids000067

What is the molecular formula of the compound?

The molecular formula of the compound is C51H40N6O23S6.

What is the molecular weight of the compound?

The molecular weight of the compound is 1297.3 g/mol.

What is the IUPAC name of the compound?

The IUPAC name of the compound is 8-[[4-methyl-3-[[3-[[3-[[2-methyl-5-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonic acid.

What is the InChIKey of the compound?

The InChIKey of the compound is FIAFUQMPZJWCLV-UHFFFAOYSA-N.

What is the CAS number of the compound?

The CAS number of the compound is 145-63-1.

What is the role of the compound as stated in the reference?

The compound has several roles including being a ryanodine receptor agonist, a GABA-gated chloride channel antagonist, an apoptosis inhibitor, an antineoplastic agent, an angiogenesis inhibitor, a purinergic receptor P2 antagonist, and a trypanocidal drug.

What is the description of the compound?

The compound is a member of the class of phenylureas and is an activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels. It has been used for the treatment of human African trypanosomiasis for over 100 years.

How is the compound used in the treatment of African trypanosomiasis?

The compound has been used parenterally in the treatment of African trypanosomiasis. It has been shown to have potent antineoplastic properties.

What are the synonyms of the compound?

The synonyms of the compound include suramin, Naganol, Suramine, Fourneau, and Farma.

Who manufactures the compound and what is its trade name?

The compound is manufactured by Bayer in Germany and is known as Germanin.