6-Amino-2-chloropurine riboside

• CAS: 146-77-0
• Catalog Number: ACM146770
• Category: Other Products
• Molecular Weight: 301.69
• Molecular Formula: C₁₀H₁₂ClN₅O₄
• Synonyms: 2-chloro-adenosin;Cl AS;Cl-Ado;6-AMINO-2-CHLOROPURINE RIBOSIDE;2-CL-ADO;2-CHLOROADENOSINE;2-CHLORO-D-ADENOSINE;2-CADO
• Melting Point: 162°C

Synthetic Use

Upstream Synthesis Route 1

• 15465-92-6

• 146-77-0

Reference: [1]Bhattarai, Sanjay; Pippel, Jan; Scaletti, Emma; Idris, Riham; Freundlieb, Marianne; Rolshoven, Georg; Renn, Christian; Lee, Sang-Yong; Abdelrahman, Aliaa; Zimmermann, Herbert; El-Tayeb, Ali; Müller, Christa E.; Sträter, Norbert
[Journal of Medicinal Chemistry, 2020, vol. 63, # 6, p. 2941 - 2957]

Downstream Synthesis Route 1

• 146-77-0

• 1839-18-5

Reference: [1] Journal of Medicinal Chemistry, 1989, vol. 32, # 5, p. 1135 - 1140
[2] Patent: WO2006/81665, 2006, A1, . Location in patent: Page/Page column 26-27

Downstream Synthesis Route 2

• 146-77-0
• 77-76-9

• 24639-06-3

Reference: [1] Nucleosides and Nucleotides, 1999, vol. 18, # 10, p. 2175 - 2191

Downstream Synthesis Route 3

• 146-77-0
• 67-64-1

• 24639-06-3

Reference: [1] Journal of Photochemistry and Photobiology B: Biology, 2016, vol. 159, p. 196 - 204

Downstream Synthesis Route 4

• 146-77-0
• 74-89-5

• 13364-95-9

Reference: [1]Bartlett; Cook; Holman; McComas; Nowoswait; Poonian; Baird-Lambert; Baldo; Marwood
[Journal of Medicinal Chemistry, 1981, vol. 24, # 8, p. 947 - 954]
[2]Schaeffer; Thomas
[Journal of the American Chemical Society, 1958, vol. 80, p. 3738,3741]

Downstream Synthesis Route 5

• 146-77-0

• 15763-11-8

Reference: [1]Tatani, Kazuya; Hiratochi, Masahiro; Nonaka, Yoshinori; Isaji, Masayuki; Shuto, Satoshi
[ACS Medicinal Chemistry Letters, 2015, vol. 6, # 3, p. 244 - 248]
[2]Schaeffer; Thomas
[Journal of the American Chemical Society, 1958, vol. 80, p. 3738,3741]

* For details of the synthesis route, please refer to the original source to ensure accuracy.