2-Amino-5-Bromo-3-methoxypyrazine

• CAS: 5900-13-0
• Catalog Number: ACM5900130
• Category: Bromine Series
• Molecular Weight: 204.02
• Molecular Formula: C₅H₆BrN₃O
• Synonyms: 5900-13-0, 5-Bromo-3-methoxypyrazin-2-amine, 2-AMINO-5-BROMO-3-METHOXYPYRAZINE, 5-Bromo-3-methoxy-2-pyrazinamine, 5-Bromo-3-methoxypyrazin-2-ylamine, 3-Bromo-5-methoxy-2-pyrazinamine, 5-bromo-3-methoxypyrazine-2-ylamine, SBB070417, AG-G-09448, PubChem23582, ACMC-1AYOS, JSPY-st000218, KSC269C6P, AGN-PC-00781S, CTK1G9167, MolPort-003-823-967, Pyrazinamine, 5-bromo-3-methoxy-, ACN-S003879, ANW-33112, RW2332
• IUPAC Name: 5-bromo-3-methoxypyrazin-2-amine
• Canonical SMILES: COC1=NC(=CN=C1N)Br
• InChI Key: QDFJJHGAODFQMN-UHFFFAOYSA-N
• Boiling Point: 262ºC
• Melting Point: 138ºC
• Flash Point: 112ºC
• Density: 1.723
• Exact Mass: 202.96900
• H-Bond Acceptor: 4
• H-Bond Donor: 1

Synthetic Use

Upstream Synthesis Route 1

• 124-41-4
• 24241-18-7

• 5900-13-0

Reference: [1] ACS Medicinal Chemistry Letters, 2017, vol. 8, # 9, p. 981 - 986
[2] Bioorganic and Medicinal Chemistry, 2001, vol. 9, # 5, p. 1149 - 1154
[3] Patent: US2013/210818, 2013, A1, . Location in patent: Paragraph 0384
[4] Patent: WO2014/68171, 2014, A1, . Location in patent: Page/Page column 27
[5] Patent: WO2009/115572, 2009, A2, . Location in patent: Page/Page column 116

Upstream Synthesis Route 2

• 67-56-1
• 24241-18-7

• 5900-13-0

Reference: [1] Organic and Biomolecular Chemistry, 2017, vol. 15, # 2, p. 373 - 378

Upstream Synthesis Route 3

• 124-41-4
• 87444-39-1

• 5900-13-0

Reference: [1]Australian Journal of Chemistry,1983,vol. 36,p. 983 - 992

Downstream Synthesis Route 1

• 5900-13-0

• 4774-10-1

Reference: [1] ACS Medicinal Chemistry Letters, 2017, vol. 8, # 9, p. 981 - 986

Downstream Synthesis Route 2

• 13176-46-0
• 5900-13-0

• 77112-58-4

Reference: [1]Farmaco, Edizione Scientifica,1981,vol. 36,p. 61 - 80

Downstream Synthesis Route 3

• 54260-84-3
• 5900-13-0

• 144294-22-4
• 144294-30-4
• 144294-29-1

Reference: [1]Il Farmaco,1992,vol. 47,p. 919 - 930

* For details of the synthesis route, please refer to the original source to ensure accuracy.