Vorinostat

• CAS: 149647-78-9
• Catalog Number: ACM149647789
• Category: Inhibitors
• Molecular Weight: 264.32
• Molecular Formula: C14H20N2O3
• Description: Vorinostat (rINN) also known as suberanilohydroxamic acid (suberoyl+anilide+hydroxamic acid abbreviated as SAHA) is a member of a larger class of compounds that inhibit histone deacetylases (HDAC). Histone deacetylase inhibitors (HDI) have a broad spectrum of epigenetic activities.Vorinostat is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL) when the disease persists, gets worse, or comes back during or after treatment with other medicines. The compound was developed by Columbia University chemist Ronald Breslow and Memorial Sloan-Kettering researcher Paul Marks.
• Synonyms: Suberoylanilidehydroxamic Acid;N-Hydroxy-N’-phenyloctanediamide;Vorinostat/SAHA;Suberoylanilide Hydroxamic Acid
• Melting Point: 161-162ºC
• Density: 1.174 g/cm³
• Appearance: White crystalline solid
• Hazard Codes: T; Xn
• Hazard Statements: T
• HS Code: 29349990
• LogP: 2.93500
• MDL Number: MFCD00945317
• PSA: 78.43
• Refractive Index: 1.566
• RIDADR: UN 2265 3/PG 3
• Safety Description: 53-36/37-45
• Supplemental Hazard Statements: H341-H360
• Symbol: GHS08
• WGK Germany: 3

Custom Q&A

What is the molecular formula of Vorinostat?

The molecular formula of Vorinostat is C14H20N2O3.

What is the molecular weight of Vorinostat?

The molecular weight of Vorinostat is 264.32 g/mol.

What is the IUPAC name of Vorinostat?

The IUPAC name of Vorinostat is N'-hydroxy-N-phenyloctanediamide.

What is the InChI of Vorinostat?

The InChI of Vorinostat is InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18).

What is the InChIKey of Vorinostat?

The InChIKey of Vorinostat is WAEXFXRVDQXREF-UHFFFAOYSA-N.

What is the canonical SMILES of Vorinostat?

The canonical SMILES of Vorinostat is C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO.

What is the CAS number of Vorinostat?

The CAS number of Vorinostat is 149647-78-9.

What is the UNII of Vorinostat?

The UNII of Vorinostat is 58IFB293JI.

What is the ChEMBL ID of Vorinostat?

The ChEMBL ID of Vorinostat is CHEMBL98.

What is the Wikipedia page of Vorinostat?

The Wikipedia page of Vorinostat is "Vorinostat".